Patterns, Variability, and Predictors of Urinary Triclosan Concentrations during Pregnancy and Childhood

Environmental Science & Technology
Shaina L StacyJoseph M Braun

Abstract

Exposure to triclosan, an antimicrobial used in many consumer products, is ubiquitous in the United States, yet only limited data are available on the predictors and variability of exposure, particularly in children. We examined the patterns, variability, and predictors of urinary triclosan concentrations in 389 mother-child pairs enrolled in the Health Outcomes and Measures of the Environment Study from 2003 to 2006. We quantified triclosan in 3 urine samples collected from women between 16 weeks of pregnancy and birth and 6 urine samples collected from children between the ages of 1-8 years. For maternal and child samples, we calculated intraclass correlation coefficients (ICCs) to assess triclosan reproducibility and identified sociodemographic predictors of triclosan. Among 8 year old children, we examined associations between triclosan and personal-care product use. We detected triclosan in >70% of urine samples. Median maternal triclosan varied across pregnancy from 17 to 11 ng/mL, while in children, median concentrations increased from 3.6 to 17 ng/mL over the first 4 years of life, declining slightly at later ages. Triclosan reproducibility was fair to good during pregnancy and for child samples taken weeks apart (ICCs ...Continue Reading

References

May 1, 1972·Clinica Chimica Acta; International Journal of Clinical Chemistry·K Larsen
Oct 30, 2004·Journal of Toxicology and Environmental Health. Part a·Hyun Jung Koo, Byung Mu Lee
Jun 22, 2005·Annals of Epidemiology·Abla Mehio-SibaiHaroutune K Armenian
Sep 6, 2006·Journal of Toxicology and Environmental Health. Part a·Gunilla Sandborgh-EnglundJan Ekstrand
Sep 30, 2006·The Science of the Total Environment·Mats AllmyrGunilla Sandborgh-Englund
Mar 13, 2008·Environmental Health Perspectives·Antonia M CalafatLarry L Needham
May 15, 2009·Environmental Health Perspectives·Antonia M CalafatRuss Hauser
Mar 24, 2010·Environmental Health Perspectives·Mary S WolffUNKNOWN Breast Cancer and Environment Research Centers
Apr 10, 2010·Critical Reviews in Toxicology·Joseph V RodricksAnnette M Shipp
Jan 15, 2011·Environmental Health Perspectives·Tracey J WoodruffJackie M Schwartz
Mar 29, 2011·Environment International·Lidia CasasUNKNOWN INMA Project
Apr 5, 2011·Journal of Applied Toxicology : JAT·Andrea B Dann, Alice Hontela
Sep 6, 2013·Environmental Health Perspectives·Carol Potera
Jan 8, 2014·Reproduction : the Official Journal of the Society for the Study of Fertility·Hanne FrederiksenAnna-Maria Andersson
Jan 30, 2014·Journal of Exposure Science & Environmental Epidemiology·Randi J BertelsenMatthew P Longnecker
Jun 28, 2014·Environmental Science & Technology·Benny F G PyckeRolf U Halden
Jul 26, 2014·Epidemiology·Claire PhilippatUNKNOWN EDEN Study Group
Dec 9, 2014·The Science of the Total Environment·Tye E ArbuckleGeorge Tawagi
Dec 11, 2014·Environmental Health Perspectives·Tye E ArbuckleWilliam D Fraser
May 27, 2015·International Journal of Hygiene and Environmental Health·Lorelle WeissCarly Lang
Jul 2, 2015·Environmental Health Perspectives·Antonia M CalafatMary S Wolff
Jul 4, 2015·International Journal of Environmental Health Research·Claudia TwumYudan Wei
Mar 24, 2016·International Journal of Epidemiology·Joseph M BraunBruce P Lanphear
May 7, 2016·Environmental Science & Technology·Shaina L StacyJoseph M Braun
Nov 20, 2016·Nature Reviews. Endocrinology·Joseph M Braun
Apr 13, 2017·Environmental Health : a Global Access Science Source·Megan E RomanoJoseph M Braun
Jun 1, 2016·Current Epidemiology Reports·Antonia M Calafat

❮ Previous
Next ❯

Citations

Nov 21, 2019·Current Environmental Health Reports·Medina S Jackson-BrowneJoseph M Braun
Jan 30, 2019·Journal of Exposure Science & Environmental Epidemiology·Traci N BetheaLauren A Wise
May 5, 2018·Environmental Health Perspectives·Medina S Jackson-BrowneJoseph M Braun
Apr 13, 2020·International Journal of Hygiene and Environmental Health·Dorothy NakiwalaUNKNOWN SEPAGES study group

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Exposure Science & Environmental Epidemiology
Randi J BertelsenMatthew P Longnecker
International Journal of Hygiene and Environmental Health
Lorelle WeissCarly Lang
© 2022 Meta ULC. All rights reserved