Jan 1, 1977

PBS-soluble substances with blood group activity from human epidermis and dermis

Acta Dermato-venereologica
L A DiazR E Jordon

Abstract

Phosphate-buffered saline (PBS) soluble extracts of human epidermis and dermis from secretor donors contain products with blood group antigenic activity. The predominant blood group in a sample was the same as the red cell phenotype of the donor. H substance activity was present in all PBS-soluble products (from A, B and O donors). By gel filtration chromatography on a Bio-Gel A-1.5 m column; the epidermal and dermal PBS-soluble blood group substances fractionate in the void volume.

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Mentioned in this Paper

Hemagglutination Inhibition Tests
Immunofluorescence Assay
Ampholytes
Skin
Sodium Chloride, (24)NaCl
Orthophosphate
Molecular Sieve Chromatography
Immunodiffusion Measurement
Epidermis
Spina Bifida Occulta

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