(P,C) Cyclometalated Gold(III) Complexes: Highly Active Catalysts for the Hydroarylation of Alkynes

Angewandte Chemie
Charlie BlonsDidier Bourissou

Abstract

The first catalytic application of well-defined (P,C) cyclometalated gold(III) complexes is reported. The bench-stable bis(trifluoroacetyl) complexes 2 a,b perform very well in the intermolecular hydroarylation of alkynes. The reaction is broad in scope, it proceeds within few hours at 25 °C at catalytic loadings of 0.1-5 mol %. The electron-rich arene adds across the C≡C bond with complete regio- and stereo-selectivity. The significance of well-defined gold(III) complexes and ligand design are highlighted in a powerful but challenging catalytic transformation.

References

Sep 3, 2008·Chemical Society Reviews·Vivian Wing-Wah Yam, Eddie Chung-Chin Cheng
Nov 26, 2010·Chemical Society Reviews·Tanya C Boorman, Igor Larrosa
Jun 16, 2011·Chemical Communications : Chem Comm·Chi-Ming Che, Raymond Wai-Yin Sun
Jun 17, 2011·Chemistry : a European Journal·Matthew N HopkinsonVéronique Gouverneur
Jun 28, 2011·Dalton Transactions : an International Journal of Inorganic Chemistry·Catherine Bronner, Oliver S Wenger
Jul 21, 2011·Angewandte Chemie·Pauline GualcoDidier Bourissou
Aug 27, 2013·Journal of the American Chemical Society·Nicolas LassauqueDidier Bourissou
Dec 7, 2013·Angewandte Chemie·Maximilian JoostDidier Bourissou
Jan 18, 2014·Journal of the American Chemical Society·Johannes GuentherDidier Bourissou
Mar 8, 2014·Chemical Society Reviews·Renso Visbal, M Concepción Gimeno
May 9, 2014·Angewandte Chemie·Hendrik TinnermannManuel Alcarazo
Jun 20, 2014·Journal of the American Chemical Society·Eirin LangsethMats Tilset
Sep 4, 2014·Dalton Transactions : an International Journal of Inorganic Chemistry·Christine HahnSamuel Adeosun
Oct 1, 2014·Journal of the American Chemical Society·Maximilian JoostDidier Bourissou
Oct 30, 2014·Angewandte Chemie·Feriel RekhroukhDidier Bourissou
Mar 3, 2015·Angewandte Chemie·Maximilian JoostDidier Bourissou
Apr 7, 2015·Chemical Reviews·Ruth Dorel, Antonio M Echavarren
Jan 16, 2016·Angewandte Chemie·Maximilian JoostDidier Bourissou
Feb 3, 2016·Angewandte Chemie·Feriel RekhroukhDidier Bourissou
Jun 3, 2016·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Andrea BiffisMarco Baron
Aug 17, 2016·Accounts of Chemical Research·Manuel Alcarazo
Aug 18, 2016·Journal of the American Chemical Society·Feriel RekhroukhDidier Bourissou
Sep 30, 2016·Angewandte Chemie·Roopender Kumar, Cristina Nevado
Jul 1, 2017·Chemical Science·Feriel RekhroukhDidier Bourissou
Aug 7, 2017·Angewandte Chemie·Anthony PujolNicolas Mézailles
Sep 12, 2017·Angewandte Chemie·Luca RocchigianiManfred Bochmann
Sep 20, 2017·Nature Communications·Abdallah ZeineddineDidier Bourissou
Dec 6, 2017·Angewandte Chemie·Jessica Rodriguez, Didier Bourissou
Jun 2, 2018·Dalton Transactions : an International Journal of Inorganic Chemistry·Charlie BlonsDidier Bourissou

❮ Previous
Next ❯

Citations

Jun 22, 2019·Chemical Communications : Chem Comm·Miquel NavarroDidier Bourissou
Sep 22, 2019·Angewandte Chemie·Lewis C WilkinsFrançois P Gabbaï
Nov 7, 2019·Angewandte Chemie·Jessica RodriguezDidier Bourissou
Sep 16, 2020·Dalton Transactions : an International Journal of Inorganic Chemistry·Maryne DuvalDidier Bourissou
Sep 22, 2020·Angewandte Chemie·Eric R KingJason David Azoulay
Nov 11, 2020·Inorganic Chemistry·Ann Christin ReiersølmoenAnne Fiksdahl
Jun 30, 2019·Inorganic Chemistry·Sailajah GukathasanSamuel G Awuah
Aug 28, 2021·Chemical Reviews·Tomáš NeveselýRyan Gilmour
Sep 23, 2020·The Journal of Organic Chemistry·Fen Wang, Qingxi Meng

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.