PMID: 42808Oct 1, 1979

PCP (phencyclidine): an update

Journal of Psychedelic Drugs
R E Garey


The steady rise in the promiscuous use of phencyclidine (PCP) as a "recreational" drug has recently gained nationwide attention because of the numerous violent and/or bizarre incidents caused by the use of this drug. Because the media often exaggerate reports of bizarre and violent behavior to make a "good" story, the potential PCP user may be tempted to ignore the media warnings. In the case of PCP, however exaggerated the story, a real danger does exist. So, despite numerous newspaper, radio and television warnings about the possible consequences of PCP use and abuse, the incidence of toxic reactions continues to climb. In many cases PCP is sold as other drugs, particularly THC, and in various colored capsules, tablets, liquids and crystals which may explain the increased usage despite the numerous warnings against its use. The advances in laboratory techniques and chemical processess have enabled the clandestine chemist to prepare relatively pure PCP and thus eliminate many of the toxic side effects due to impurities in the drug. In addition, 30 or more psychoactive PCP analogues have been developed and are starting to make an appearance on the street. PCP is perhaps the most potent psychotomimetic compound known at the pres...Continue Reading


Dec 8, 2011·Psychopharmacology·Barbara LangenNorbert Hoefgen
Jan 1, 1983·Brain Research Bulletin·M Matsuzaki, K C Dowling
Jan 1, 1988·Journal of Substance Abuse Treatment·J M HerreraJ Sramek
May 7, 1998·European Journal of Pharmacology·K Krebs-ThomsonM A Geyer
Nov 18, 2000·Behavioural Brain Research·Y MiyamotoT Nabeshima
Dec 6, 1980·British Medical Journal
Mar 26, 2014·Nature Reviews. Nephrology·Randy L Luciano, Mark A Perazella
Oct 1, 1982·The International Journal of the Addictions·B L Davis
Oct 1, 1982·Journal of Toxicology. Clinical Toxicology·A M Khajawall, G M Simpson
Aug 22, 2015·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Matilda BäckbergAnders Helander
Mar 29, 2014·Drug Testing and Analysis·Hamilton Morris, Jason Wallach
Oct 1, 1993·Forensic Science International : Synergy·A C AllenS Calderon
Feb 1, 1987·The Journal of Pediatrics·R H SchwartzM Riddile
Feb 1, 1986·Oral Surgery, Oral Medicine, and Oral Pathology·S O IsaacsJ A Washington
Aug 22, 2016·Brain Research·Jennifer J Donegan, Daniel J Lodge
Feb 1, 1983·Psychological Reports·P T GriffinJ W Goethe
Dec 6, 1980·British Medical Journal


Jan 1, 1976·Clinical Toxicology·B J FaumanP Rosen
Jul 1, 1977·The American Journal of Psychiatry·B J CarrollE Kokmen
Jan 1, 1978·Clinical Toxicology·R S Burns, S E Lerner
Aug 1, 1978·NIDA Research Monograph·R C Petersen, R C Stillman
May 5, 1978·Science·C A TammingaJ M Davis
Sep 1, 1979·Journal of the American Podiatry Association·R IstellE Buchbinder
Oct 1, 1979·Journal of Psychedelic Drugs·C Russ, D Wong
Oct 1, 1979·Journal of Psychedelic Drugs·S W Twemlow, W T Bowen
Jul 1, 1979·Journal of Psychedelic Drugs·K A Carlson
Apr 15, 1978·European Journal of Pharmacology·R L Balster, L D Chait
Jun 1, 1978·JACEP·B J Fauman
Jan 1, 1978·The American Journal of Drug and Alcohol Abuse·G G De Angelis, E Goldstein
Jan 1, 1976·Clinical Toxicology·R S Burns, S E Lerner
Jan 1, 1976·Clinical Toxicology·R L Balster, L D Chait
Jul 1, 1977·The American Journal of Psychiatry·R C SmithJ M Davis
Jan 1, 1976·Clinical Toxicology·P V Luisada, B I Brown
Jan 1, 1976·Clinical Toxicology·G D LundbergS H Montgomery
Jan 1, 1975·Clinical Toxicology·R C GuptaG D Lundberg
Nov 3, 1975·JAMA : the Journal of the American Medical Association·T G TongU Boerner
Nov 13, 1975·JAMA : the Journal of the American Medical Association·C B LidenC E Costello
Oct 31, 1974·The New England Journal of Medicine·A V Daftery
Nov 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·S MaayaniM Sokolovsky
Feb 1, 1973·Archives of General Psychiatry·D S JanowskyH J Sekerke
Aug 1, 1973·European Journal of Pharmacology·O A Nedergaard
Apr 8, 1971·The New England Journal of Medicine·S H Schnoll, W H Vogel
Apr 8, 1971·The New England Journal of Medicine·C E Reier
Jun 1, 1969·Tetrahedron Letters·Y Ban, I Iijima
Mar 1, 1959·A.M.A. Archives of Neurology and Psychiatry·E D LUBYR KELLEY
Jun 1, 1961·Canadian Psychiatric Association Journal·T A BANH E LEHMANN
Dec 1, 1960·Comprehensive Psychiatry·B D COHENJ S GOTTLIEB
Jul 1, 1960·The Journal of Mental Science·B M DAVIES, H R BEECH
Mar 1, 1965·Journal of Medicinal Chemistry·V H MADDOXR F PARCELL
Oct 1, 1959·British Journal of Anaesthesia·M JOHNSTONES BAIGEL
Jun 21, 1974·Science·S H SnyderD Greenberg

Related Concepts

Phencyclidine Hydrobromide
Chronic Disease
Psychoses, Drug
Drug-Induced Liver Injury
Dopamine Receptor
Social Ecology
Dose-Response Relationship, Drug

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Sexual Dimorphism in Neurodegeneration

There exist sex differences in neurodevelopmental and neurodegenerative disorders. For instance, multiple sclerosis is more common in women, whereas Parkinson’s disease is more common in men. Here is the latest research on sexual dimorphism in neurodegeneration

HLA Genetic Variation

HLA genetic variation has been found to confer risk for a wide variety of diseases. Identifying these associations and understanding their molecular mechanisms is ongoing and holds promise for the development of therapeutics. Find the latest research on HLA genetic variation here.

Super-resolution Microscopy

Super-resolution microscopy is the term commonly given to fluorescence microscopy techniques with resolutions that are not limited by the diffraction of light. Here are the latest discoveries pertaining to super-resolution microscopy.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.

Brain Lower Grade Glioma

Low grade gliomas in the brain form from oligodendrocytes and astrocytes and are the slowest-growing glioma in adults. Discover the latest research on these brain tumors here.

CD4/CD8 Signaling

Cluster of differentiation 4 and 8 (CD8 and CD8) are glycoproteins founds on the surface of immune cells. Here is the latest research on their role in cell signaling pathways.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.