PMID: 3754252Feb 1, 1986Paper

PD 116,152, a novel phenazine antitumor antibiotic. Discovery, fermentation, culture characterization and biological activity

The Journal of Antibiotics
J B TunacW E Dobson

Abstract

A novel phenazine antitumor antibiotic is described, produced by Streptomyces lomondensis subsp. galanosa NRRL 15738. The antibiotic is selectively active versus the bacterium Streptococcus pneumoniae (MIC less than 0.46 microgram/ml); the antitumor activity versus murine P388 leukemia is T/C 149.

Citations

Jun 7, 2018·International Journal of Cancer. Journal International Du Cancer·Jun AraiNaoya Kato
Jan 1, 1991·Critical Reviews in Biotechnology·C M Franco, L E Coutinho
Feb 18, 2012·Natural Product Reports·A CimminoR Kiss
Mar 11, 2004·Chemical Reviews·Jane Buus Laursen, John Nielsen
Jul 11, 2012·Journal of Natural Products·Birgit OhlendorfJohannes F Imhoff

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