Pd/Cu Cocatalyzed Oxidative Tandem C-H Aminocarbonylation and Dehydrogenation of Tryptamines: Synthesis of Carbolinones

The Journal of Organic Chemistry
Hui HanJi-Bao Xia

Abstract

The Pd/Cu cocatalyzed oxidative tandem C-H aminocarbonylation and dehydrogenation was developed, affording carbolinones with molecular oxygen as the terminal oxidant. Natural product strychnocarpine and its derivatives were prepared conveniently using this strategy.

References

Apr 22, 1992·European Journal of Pharmacology·J StrömbomW Rolfsen
Feb 28, 2004·Organic Letters·Rachel N SonnenscheinPhillip Crews
May 29, 2004·Journal of Natural Products·Nathaniel L SegravesPhillip Crews
Nov 4, 2004·Journal of the American Chemical Society·Kazuhiko OritoMasao Tokuda
Jan 18, 2005·Chemical Communications : Chem Comm·Shinichiro OhashiYasutaka Ishii
Mar 10, 2005·Chemical Reviews·Julia-Christina WasilkeGuillermo C Bazan
Jun 25, 2005·Journal of Natural Products·Arzu Küçükosmanogiu BahçeevliDavid G I Kingston
Sep 9, 2005·Organic Letters·Kimberly N White, Joseph P Konopelski
Jan 16, 2007·Organic Letters·Thomas LindelPetra Böhrer
Sep 25, 2007·Angewandte Chemie·Dirk HollmannMatthias Beller
Oct 7, 2008·Journal of the American Chemical Society·Ramesh Giri, Jin-Quan Yu
Dec 23, 2008·Journal of the American Chemical Society·Zheng-Hui GuanXumu Zhang
Jan 7, 2009·Organic Letters·Tobias Ankner, Göran Hilmersson
Jan 27, 2009·Angewandte Chemie·Chris E HouldenKevin I Booker-Milburn
Feb 25, 2009·Journal of the American Chemical Society·David B C Martin, Christopher D Vanderwal
Mar 28, 2009·Planta medica·Xu-Jia HuXiao-Jiang Hao
Apr 1, 2009·Chemical Communications : Chem Comm·Heloise Brice, Jonathan Clayden
Aug 19, 2010·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Guowu LinTao Lu
Aug 27, 2010·Angewandte Chemie·Xiao-Feng WuMatthias Beller
Oct 12, 2010·Dalton Transactions : an International Journal of Inorganic Chemistry·Hu LiZhang-Jie Shi
Nov 17, 2010·Chemical Communications : Chem Comm·Blanca LópezJaume Granell
Nov 19, 2010·Journal of the American Chemical Society·Eun Jeong YooJin-Quan Yu
Apr 29, 2011·Bioorganic & Medicinal Chemistry·Shi-Jin QuDa-Yuan Zhu
May 6, 2011·Journal of the American Chemical Society·Nao HasegawaNaoto Chatani
Jun 30, 2011·Organic Letters·K C NicolaouJochen Becker
Sep 14, 2011·Organic Letters·Joe W WrigglesworthKevin I Booker-Milburn
Oct 18, 2011·Chemical Communications : Chem Comm·Huoji ChenHuanfeng Jiang
Oct 19, 2011·Chemical Communications : Chem Comm·Ya DuTomislav Rovis
Oct 27, 2011·Chemical Communications : Chem Comm·Rui LangFuwei Li
Jun 6, 2012·Journal of the American Chemical Society·Pan XieHanmin Huang
Oct 12, 2012·Journal of the American Chemical Society·Zheng-Hui GuanZhi-Hui Ren

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Citations

Aug 28, 2020·Chemical Communications : Chem Comm·Zheng-Yang GuJi-Bao Xia
Dec 10, 2021·Chemical Communications : Chem Comm·Aleksandr VoronovNicola Della Ca

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