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PDGF enhances the protective effect of adipose stem cell-derived extracellular vesicles in a model of acute hindlimb ischemia

Scientific Reports

Dec 6, 2018

Tatiana LopatinaGiovanni Camussi

Abstract

We previously have shown that platelet-derived growth factor (PDGF) modulates the biological activity of extracellular vesicles released by adipose-derived mesenchymal stem cells (ASC-EVs). ASC-EVs may interact with blood and vessel cells by transferring proteins and nucleic acids and r...read more

Mentioned in this Paper

Entire Hindlimb
Tumor Necrosis Factor-alpha
In Vivo
Interferons
Interleukin-1 beta
Hindlimb
Recombinant Interleukin-10
Recombinant Interleukin-17
Immunomodulators
Ischemia
1
11

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PDGF enhances the protective effect of adipose stem cell-derived extracellular vesicles in a model of acute hindlimb ischemia

Scientific Reports

Dec 6, 2018

Tatiana LopatinaGiovanni Camussi

PMID: 30514962

DOI: 10.1038/s41598-018-36143-3

Abstract

We previously have shown that platelet-derived growth factor (PDGF) modulates the biological activity of extracellular vesicles released by adipose-derived mesenchymal stem cells (ASC-EVs). ASC-EVs may interact with blood and vessel cells by transferring proteins and nucleic acids and r...read more

Mentioned in this Paper

Entire Hindlimb
Tumor Necrosis Factor-alpha
In Vivo
Interferons
Interleukin-1 beta
Hindlimb
Recombinant Interleukin-10
Recombinant Interleukin-17
Immunomodulators
Ischemia
1
11

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