Peak growth velocity in infancy is positively associated with blood pressure in school-aged children

Journal of Hypertension
Elisabeth ThieringLISAplus Study Group

Abstract

Rapid growth velocity in early life may be a risk factor for obesity, elevated blood pressure, and adverse metabolic markers in childhood, but results are not consistent. We analysed the association between peak growth velocity during the first 2 years of life and blood pressure, fasting glucose and insulin at 10 years of age. A prospective German birth cohort (LISAplus) provided data on growth, blood pressure, glucose, and insulin for 1127 children up to the age of 10 years. All children had a birth weight of at least 2500 g. Growth was modelled using nonlinear mixed-effect Reed1 models. Associations between peak growth velocities and metabolic outcomes were calculated with linear regression models. Potential confounders were sequentially adjusted for. Higher peak height velocity (PHV) and peak weight velocity (PWV) in infancy were associated with significant increase in systolic blood pressure (SBP) and diastolic blood pressure (DBP) in children at 10 years. For each 10.2 cm/year [2 standard deviation (SD)] increase in PHV, SBP increased by 2.94 mmHg [95% confidence interval (CI) 1.34, 4.54] after adjustment for potential confounders including birth weight and body mass index. A 5.1 kg/year (2 SD) higher PWV was associated wi...Continue Reading

References

Nov 18, 2000·Hypertension·J ErikssonD Barker
Oct 3, 2002·The European Respiratory Journal·J HeinrichUNKNOWN LISA Study Group
May 4, 2007·Journal of Human Hypertension·J W MinH Park
May 23, 2009·Journal of Hypertension·Vera A A van HoutenVincent W V Jaddoe
Jan 12, 2011·Circulation·Giacomo D SimonettiElke Wühl
Jan 1, 1992·American Journal of Human Biology : the Official Journal of the Human Biology Council·Kirsten B SimondonAndre Cornu

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Citations

Nov 14, 2013·Journal de gynécologie, obstétrique et biologie de la reproduction·G Gascoin, C Flamant
Aug 24, 2012·PloS One·Marieke L A de HoogTanja G M Vrijkotte
Mar 13, 2014·Current Problems in Pediatric and Adolescent Health Care·Roya Kelishadi, Parinaz Poursafa
May 3, 2014·Pediatric Diabetes·Andreas BeyerleinAnette-Gabriele Ziegler
Jun 27, 2015·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·G Gascoin, C Cipierre
Dec 17, 2019·Science Advances·Alexessander Couto AlvesUNKNOWN Early Growth Genetics (EGG) Consortium
Mar 18, 2020·Pediatric Obesity·Xuedi LiUNKNOWN TARGet Kids! Collaboration
Jun 16, 2015·Pediatric Pulmonology·Flexeder ClaudiaHolger Schulz
Aug 18, 2017·European Journal of Epidemiology·Heinz-Erich Wichmann
Dec 1, 2020·Childhood Obesity·Xuedi LiUNKNOWN TARGet Kids! Collaboration

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