PMID: 9183283May 1, 1997Paper

Pearls, pitfalls, and updates in toxicology

Emergency Medicine Clinics of North America
M Kirk, S Pace

Abstract

Pearls and pitfalls learned from our practical experiences caring for poisoned patients are presented. Clinical pearls include the following: using diagnostic tests to detect end-organ toxicity, applying physiologic principles to the management of hemodynamically unstable poisoned patients, and dealing with psychologic injuries from hazardous materials incidents. Recognizing serious complications from poisoning and adverse drug effects, including the serotonin syndrome, are offered as pitfalls. Pharmaceutical companies are rapidly developing and marketing new therapies. Therefore, updates on the evolving role of NAC as an antidote for acetaminophen poisoning, new psychotropic medications, and new antidotes were included in this article. These pearls, pitfalls, and updates are intended to provide practical information that is readily applicable to the clinical practice of emergency medicine.

References

Nov 3, 1979·British Medical Journal·L F PrescottA T Proudfoot
Oct 1, 1978·Archives of Internal Medicine·P A GabowR W Schrier
Sep 6, 1976·JAMA : the Journal of the American Medical Association·D J Powner
Dec 1, 1976·Annals of Internal Medicine·R J AndersonR W Schrier
Nov 1, 1992·Annals of Emergency Medicine·R D HerrM S Linscott
Mar 1, 1992·The American Journal of Emergency Medicine·D J BorysE P Krenzelok
Oct 1, 1991·Annals of Emergency Medicine·M J SmilksteinB H Rumack
Nov 1, 1990·The American Journal of Emergency Medicine·K S MerigianM C Rashkin
Jun 1, 1991·The American Journal of Psychiatry·H Sternbach
Sep 1, 1990·The Journal of Emergency Medicine·M J Smilkstein
Nov 1, 1990·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·L A Brawn, C M Castleden
Aug 1, 1989·Annals of Emergency Medicine·D D VernonJ M Dean
Jun 24, 1989·BMJ : British Medical Journal·W BurrA Judd
Apr 1, 1989·Annals of Emergency Medicine·T R WolfeD E Rollins
Mar 1, 1989·Medical Toxicology and Adverse Drug Experience·C Köppel
Aug 1, 1989·The American Review of Respiratory Disease·J E Rinaldo, J V Snyder
Oct 1, 1989·Annals of Emergency Medicine·S C CurryD Connor
Mar 20, 1989·The Medical Journal of Australia·A H DawsonJ McEwen
Jun 1, 1985·Annals of Emergency Medicine·K KuligB H Rumack
Aug 1, 1987·Annals of Internal Medicine·E B LarsonB V Reifler
Apr 1, 1989·Journal of the American Geriatrics Society·H G Colt, A P Shapiro
Sep 1, 1988·Progress in Cardiovascular Diseases·W M JackmanR Lazzara
Apr 9, 1988·British Medical Journal·T G ShortD C Galletly
Jan 1, 1988·Medical Toxicology and Adverse Drug Experience·A Amdisen
Mar 24, 1988·The New England Journal of Medicine·D A Asch, R M Parker
Jul 1, 1988·Annals of Emergency Medicine·A NiceD O Hryhorczuk
Mar 1, 1986·Annals of Internal Medicine·L B SeeffS B Benjamin
Apr 17, 1987·Science·P Slovic
May 1, 1986·The American Journal of Cardiology·J T NiemannM M Laks
Jun 1, 1985·Annals of Emergency Medicine·S C CurryR Armstead
May 1, 1985·The American Journal of Emergency Medicine·S C Curry, D B Kunkel
Nov 30, 1974·British Medical Journal·D P Southall, S M Kilpatrick
Dec 8, 1983·The New England Journal of Medicine·M J BrownM B Murphy
Mar 9, 1984·JAMA : the Journal of the American Medical Association·C BaumJ K Jones
Aug 1, 1982·The Journal of Pediatrics·R M Perkin, D L Levin

❮ Previous
Next ❯

Citations

Mar 21, 2007·Bulletin of Experimental Biology and Medicine·I A GamaleiS Yu Khaitlina
Mar 29, 2006·Clinics in Laboratory Medicine·Bryan S Judge
Oct 18, 2005·The Medical Clinics of North America·Bryan S Judge
Aug 26, 1998·Lancet·N DelantyJ A French
Jun 13, 2021·The Veterinary Clinics of North America. Equine Practice·Julie E Dechant

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.