PEComa of the nasal cavity with worrisome histologic features and benign behavior: a case report

The Annals of Otology, Rhinology, and Laryngology
Corso BoccioliniDanilo Dall'Olio

Abstract

PEComas (perivascular epithelioid cell tumors) are a family of neoplastic lesions that share overlapping ultrastructure and morphological and immunohistochemical appearance and include angiomyolipoma, lymphangioleiomyomatosis, and clear cell "sugar" tumor of the lung, as well as similar tumors that occur in a variety of visceral, cutaneous, and soft tissue sites throughout the body. A 40-year-old woman came to medical attention because of epistaxis and because of unilateral nasal obstruction of 3 months' duration. Endoscopic examination revealed a well-demarcated exophytic lesion attached to the anterior portion of the middle turbinate. The lesion was superficially located, and therefore amenable to complete surgical excision. Seven years after surgery, the patient is alive and well, without evidence of local recurrence or metastastic disease. Based on morphological and immunohistochemical appearance, a diagnosis of PEComa with worrisome histologic features was rendered. In the present study, we describe a PEComa that occurred in the nasal cavity and discuss the behavior of this entity. The importance of recognizing this disease will ensure its consideration in the differential diagnosis of tumors of the head that have similar ...Continue Reading

References

Feb 8, 2003·International Journal of Surgical Pathology·S S BanerjeeJ Rosai
Dec 20, 2005·Histopathology·J L Hornick, C D M Fletcher
Feb 19, 2008·The American Journal of Surgical Pathology·Bernadette LieglChristopher D M Fletcher
Sep 30, 2009·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·John PanelosAlessandro Franchi
Oct 1, 2009·Pathology International·Naoto KurodaGang-Hong Lee
Oct 27, 2010·The American Journal of Surgical Pathology·Kyoko Yamashita, Christopher D M Fletcher

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Citations

Dec 24, 2016·The American Journal of Surgical Pathology·Stephanie M McGregorThomas Krausz
Mar 19, 2020·Clinical Case Reports·Michael I DoughertyJose L Mattos

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