PMID: 25764842Jan 1, 2014Paper

Peculiar features of forming radiation effects in inbred populations of Drosophila melanogaster differing in cytotype

Radiatsionnaia biologiia, radioecologiia
E A Iushkova, V G Zaĭnullin

Abstract

A comparative evaluation of the sensitivity of inbred wild-type flies differing in the cytotype to the action of low-intensity radiation of different duration was conducted taking into account the integral parameters of survival. The strong dependence of the frequency of radiation-induced DNA damage (in the neutralpH version) to the cells of individuals on the dose of low-intensity radiation and stages of spermatogenesis was established. The hyper-radiosensitivity was found in the individuals of Charolles (R-cytotype), Harwich (P-cytotype), and Oregon-R (H-cytotype) strains irradiated during the early stages of spermatogenesis (spermatogonia-spermatocytes) and containing in their genotype transposons Bari 1, P and hobo, respectively. While drosophila line Canton-S exhibited dysgenetic properties against the background of several cytotypes (E, I and M), the effect of hormesis was identified under the same experimental conditions. With the increase in the dose of low-intensity irradiation, the frequency of the DNA damage either increased (for Canton-S) or reduced (for Harwich and Charolles). At that, the profile of fertility and. survival of wild-type stocks studied was maintained at a significantly high level. The important role...Continue Reading

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