Abstract
Accurate assessment of the value of asthma interventions in pediatric clinical trials is an essential step toward the improvement of the treatment of this disorder in children. Conventional pulmonary function measures can be infeasible and unreliable in younger children, particularly for use in multisite studies. As an alternative or supplemental approach, diary questionnaires completed by the patients or their caregivers may provide valuable data regarding the efficacy of asthma interventions in pediatric clinical trials. These questionnaires, however, have routinely not been validated for use in pediatric populations. Two pediatric diary questionnaires (the child-completed Pediatric Asthma Diary [PAD] and the parent/caregiver-completed Pediatric Asthma Caregiver Diary [PACD]) were designed to evaluate asthma symptoms in children aged 6 to 14 years and 2 to 5 years, respectively. The validity of these diary questionnaires was evaluated in 2 separate prospective studies that included children who were divided into 2 asthma groups: stable (requiring no additional asthma medication) and unstable (requiring either an increase in or the addition of asthma medication). Both scales displayed significant discriminant validity, constru...Continue Reading
Citations
May 17, 2014·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Carlos E Rodríguez-MartínezGustavo Nino
Oct 1, 2015·Pediatric Pulmonology·Suelen G OliveiraRita Mattiello
Aug 17, 2018·Respiratory Research·Allison J BurbankMichelle L Hernandez
Mar 28, 2019·Global Pediatric Health·Samta Pandya
Jan 6, 2006·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Jonathan M SpergelAleksandra Bokszczanin-Knosala
Apr 17, 2010·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Karin B YeattsDarren A DeWalt
Nov 1, 2016·Clinical Pediatrics·Nathalie duRivageAlexander G Fiks
Apr 5, 2008·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Hsin-Hung ChenLi-Fan Liu
Jul 28, 2012·Journal of Medical Internet Research·David GustafsonJee-Seon Kim
Jun 3, 2018·Therapeutic Advances in Respiratory Disease·Anna PłoszczukSanjeeva Dissanayake
Oct 20, 2017·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Ozlem KeskinOmer Kalayci
Jan 22, 2015·Indoor Air·P LajoieH Schleibinger
Feb 2, 2019·Respiratory Medicine·Janusz CiółkowskiBarbara Stasiowska