Pediatric gliomatosis cerebri mimicking acute disseminated encephalomyelitis

Pediatrics
Hope T RichardJeffrey S Sosnowski

Abstract

Gliomatosis cerebri (GC) is a diffuse infiltrating glial neoplasm of astrocytic origin. GC in children is rare and difficult to diagnose, often presenting with a variety of signs and symptoms that may mimic encephalitis. We discuss here the presentation and diagnosis of GC in 2 children who were initially suspected to have acute disseminating encephalomyelitis. In this report we underscore the limitations of relying on clinical presentation and neuroimaging as well as the essential role of pathologic evaluation for the diagnosis of GC in children.

Citations

Apr 6, 2012·Current Treatment Options in Neurology·Daniela Pohl, Silvia Tenembaum
Mar 30, 2013·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·Ivan AdamecMario Habek
Sep 24, 2016·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Matthew T Brown, Frederick A Boop
Aug 5, 2015·Journal of Child Neurology·Emilie GeorgeJeffrey P Greenfield

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