Pediatric hyperglycemic hyperosmolar syndrome: diagnostic difficulties and high mortality rate

The American Journal of Emergency Medicine
Joel B CochranJoseph D Losek

Abstract

Childhood obesity has become a pandemic health care problem. A complication of childhood obesity is type 2 diabetes mellitus which has increased 10-fold in the past 20 years. A serious complication of type 2 diabetes mellitus is hyperglycemic hyperosmolar syndrome (HHS). The following case is an obese adolescent boy with a newly diagnosed HHS. The demographic and clinical characteristics of our case and those of 17 other cases from recently published small case series are presented. Of the 18 cases, there were 13 deaths (72%). The purpose of this report and literature review is to emphasize the importance of early diagnoses and treatment of pediatric HHS.

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Citations

Mar 27, 2010·International Journal of Pediatric Endocrinology·Srinivas Murthy, Rana Sharara-Chami
Aug 20, 2010·Diabetology & Metabolic Syndrome·Alfredo HalpernMarcia Nery
Aug 1, 2015·Journal of Paediatrics and Child Health·Amanda PriceBenjamin Jackson
Oct 29, 2011·Neurologic Clinics·Shashi S SeshiaVenkatraman Sadanand
Nov 3, 2010·The Journal of Pediatrics·Phil ZeitlerUNKNOWN Drugs and Therapeutics Committee of the Lawson Wilkins Pediatric Endocrine Society
Jan 29, 2010·The Journal of Pediatrics·Arlan L Rosenbloom
Dec 7, 2007·Journal of Pediatric Endocrinology & Metabolism : JPEM·Michael F CanarieWilliam V Tamborlane
Jul 1, 2012·Expert Review of Endocrinology & Metabolism·Ildiko H Koves, Catherine Pihoker
Sep 29, 2020·Frontiers in Medicine·Todd S IngAntonios H Tzamaloukas

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