Pediatric Inflammatory CNV: A Case Series from a Tertiary Referral Centre

Ocular Immunology and Inflammation
Sudha Ganesh, Arshee Ahmed

Abstract

To report a case series of pediatric inflammatory choroidal neovascularization (CNV) seen at referral uveitis clinic. Records of pediatric patients with uveitis and inflammatory CNV between January 2000 and December 2012 were analyzed. Ten eyes of seven patients were included. Mean age 12.6 years, mean follow-up 89.6 months. Three out of seven patients had bilateral CNV. Subfoveal CNV was noted in five eyes, extrafoveal CNV in three eyes and juxtafoveal and peripapillary CNV each in one eye. All patients received corticosteroids; immunosuppressives were used in three patients. Additional anti-VEGF injections were given, in six eyes, anti-VEGF and PDT in one eye and only PDT in three eyes. Pediatric inflammatory CNV though challenging, can be successfully managed with prompt therapy of the underlying uveitic disease, coupled with additional local therapy to selectively target the CNV.

References

Oct 28, 1999·Current Opinion in Ophthalmology·R F Spaide
Aug 4, 2005·Retina·Fabrizio GiansantiUgo Menchini
Oct 1, 2005·American Journal of Ophthalmology·Douglas A JabsUNKNOWN Standardization of Uveitis Nomenclature (SUN) Working Group
Mar 29, 2008·The British Journal of Ophthalmology·S Sivaprasad, A T Moore
Oct 15, 2011·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Irene C KuoWilliam Park
Mar 22, 2013·Journal of Ophthalmic Inflammation and Infection·Sonia MehtaJohn H Kempen
Jul 1, 2014·Retina·Igor KozakUNKNOWN King Khaled Eye Specialist Hospital International Collaborative Retina Study Group

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Citations

Feb 1, 2020·Ocular Immunology and Inflammation·Emmett T CunninghamManfred Zierhut

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