Abstract
Mature B-cell non-Hodgkin lymphoma (B-NHL) comprises more than 50% of all non-Hodgkin lymphoma (NHL) in children and adolescents. An official report published by the Mexican National Center for the Control and Prevention of Cancer in the Pediatric and Adolescent Populations, reported a lymphoma OS of 71% (including all Hodgkin and NHL). The Mexican Association of Pediatric Oncology and Hematology conducted a retrospective study to analyze the clinical characteristics and outcomes of children with diagnosis of B-NHL in Mexico, in order to perceive the main areas of improvement in the health care. From 1 January 2000 to 31 December 2016, 166 pediatric patients were diagnosed with B-cell NHL at the participant institutions. According to histology the outcomes were 5-year EFS 63%, for BL/BLL, and 80% DLBCL, (P = .051), 5-year PFS 81%, for BL/BLL, and 91% for DLBCL, (P = .126), and 5-year OS 71%, for BL/BLL, and 83% for DLBCL, (P = .095). Overall, 18 patients died due to acute treatment toxicity, resulting in a cumulative incidence of toxic death of 10.84% and an early death rate of 7.23%, defined as <30 days after initial treatment. In conclusion, there is an urgent need to establish an academic collaboration to create strategies t...Continue Reading
References
Feb 1, 1989·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·S B MurphyC W Berard
Jan 5, 2002·Hematological Oncology·J K Chan
Sep 24, 2004·Pediatric Blood & Cancer·G AcquatellaA Nouel
Jan 24, 2008·Pediatric Blood & Cancer·Mhamed HarifJean Lemerle
Jan 5, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Mitchell S CairoCatherine Patte
Aug 4, 2012·Journal of Pediatric Hematology/oncology·Carolina CervioGuillermo L Chantada
Sep 4, 2012·Leukemia·S GoldmanM S Cairo
Nov 6, 2012·Revista brasileira de hematologia e hemoterapia·Keyla Christy Christine Mendes Sampaio CunhaMarcos Borato Viana
Apr 11, 2013·Pediatric Hematology and Oncology·Jennifer WorchBirgit Burkhardt
Jan 7, 2014·Journal of Pediatric Hematology/oncology·Ronald D Barr
Feb 14, 2014·Pediatric Blood & Cancer·Masahito TsurusawaUNKNOWN lymphoma committee of Japanese Pediatric Leukemia/Lymphoma Study Group
Dec 3, 2014·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·M A Baena-GómezL Madero López
Mar 1, 2015·Haematologica·Anne JourdainUNKNOWN SFCE LNH Committee
Apr 15, 2015·Pediatric Hematology and Oncology·Aléine Nzazi BudiongoMichel Ntetani Aloni
Jan 9, 2018·SICOT-J·Ahmed AbdelbadieMohamed Ahmed Radwan
Jan 1, 2015·Boletín médico del Hospital Infantil de México·Sonia Fernández Cantón, Ana María Hernández Martínez
Citations
Mar 16, 2019·Science·Catherine G LamKathy Pritchard-Jones
Feb 12, 2019·British Journal of Haematology·Guillermo ChantadaScott C Howard
Dec 7, 2021·British Journal of Haematology·Maria Luisa MoletiRobin Foà
Jan 4, 2022·Pediatric Hematology and Oncology·Emine A RahimanAmita Trehan