Pediatric noncompaction patients with high spatial QRS-T angles are at increased risk for ventricular tachycardia

Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
Daniel CortezJason R Imundo

Abstract

Noncompaction cardiomyopathy (NCCM) patients may develop sustained ventricular arrhythmias (VA). Currently no known electrocardiogram (ECG) parameter has demonstrated predictive value for VA development. The spatial QRS-T angle has demonstrated ability to identify VA in other cardiomyopathy populations. A total of 39 patients with NCCM, defined by compact to non-compact ratio of >2.3 by magnetic resonance imaging, were assessed. The first ECG taken at time of MRI was assessed utilizing the heart rate, the QRS duration (QRSd), the corrected QT interval (QTc), and the spatial QRS-T angle (SPQRS-T angle, three-dimensional angle between the QRS and T-wave vectors) were assessed. Eight patients developed VA (20.5%). Median time to event was 3 months (95% CI 1.0 to 24.0 months). There were no significant differences between baseline ejection fraction or fractional shortening. Baseline median heart rate, spatial QRS-T angles, and indexed left ventricular end-diastolic volumes were all significantly higher in patients with VA development (p-value <0.05). Only heart rate and the SPQRS-T angle had significant univariate hazard ratios (HR) for VA at 1.031/beat per minute (1.001-1.071) and at a cut-off of 147 degrees the SPQRS-T angle gave...Continue Reading

References

Jul 5, 2005·Journal of the American College of Cardiology·Steffen E PetersenStefan Neubauer
Aug 22, 2006·European Journal of Clinical Investigation·Ch VoulgariN Katsilambros

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Citations

Apr 4, 2021·Journal of Clinical Medicine·Katarzyna Łuczak-Woźniak, Bożena Werner

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