Pediatric Pancreatic Tuberculosis: A Case Report and Review of the Literature

Case Reports in Pediatrics
Yajun Zhang, Yuhong Tao

Abstract

Pancreatic tuberculosis (TB) is an uncommon form of extrapulmonary TB and represents a diagnostic challenge for physicians. Pancreatic TB presents with nonspecific signs and symptoms and may mimic malignancy. However, pancreatic TB rarely occurs in children. Here, we present a case of a 5-year-old girl with pancreatic TB and markedly elevated serum cancer antigen- (CA-) 125 levels, thus raising the suspicion of malignancy, but positivity for Mycobacterium tuberculosis DNA was noted. The patient recovered after being administered standard antitubercular therapy for one year. This case suggests that clinicians should have a heightened suspicion of pancreatic TB when faced with pancreatic lesions despite the fact that increased CA-125 may indicate malignancy. Laparoscopy combined with peritoneal biopsy and polymerase chain reaction (PCR) may provide a new method to confirm the diagnosis.

References

Jan 1, 1999·European Journal of Gastroenterology & Hepatology·S D LadasS A Raptis
Jan 30, 2002·The American Journal of the Medical Sciences·Carlos Franco-ParedesRichard M Smith
Jun 12, 2003·World Journal of Gastroenterology : WJG·Feng XiaJia-Hong Dong
May 18, 2004·ANZ Journal of Surgery·John C WoodfieldNeil M Officer
Mar 1, 2012·World Journal of Gastroenterology : WJG·Somchai Meesiri
Jul 6, 2012·The American Journal of Tropical Medicine and Hygiene·Ankur AroraHitendra Garg
Sep 26, 2015·Bangladesh Medical Research Council Bulletin·N Ali Mohsin M N
Feb 18, 2016·The Indian Journal of Surgery·Poras ChaudharyMohinder P Arora

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Methods Mentioned

BETA
PCR
biopsy

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