PMID: 11918466Mar 29, 2002Paper

Pediatric partial and generalized seizures

Journal of Child Neurology
Martina Bebin

Abstract

Eight new anticonvulsant medications have been approved in the United States since 1993, offering physicians a greater range of options for treating children with partial and generalized seizures. However, pediatric neurologists have been faced with limited pediatric pharmacokinetic and pharmacodynamic information. This article reviews the newer antiepilepsy drugs-gabapentin, felbamate, lamotrigine, topiramate, oxcarbazepine, levetiracetam, and zonisamide-and summarizes what is currently known about the safety and efficacy of these drugs in treating partial and generalized seizures in the pediatric population. Further studies are needed, however, to thoroughly evaluate their efficacy and safety in children.

References

Jan 1, 1996·Neurology·J DooleyE Smith
Jan 1, 1996·Epilepsia·D O LeeM A Mikati
Nov 5, 1997·Seminars in Pediatric Neurology·G L Holmes
Mar 18, 1999·Epilepsia·M Sadler
Apr 24, 1999·Neurology·C T Lombroso
Jul 15, 2000·Clinical Neuropharmacology·B F Bourgeois
Aug 10, 2001·Journal of Long-term Effects of Medical Implants·S L BrownC M Parmentier
Jan 24, 2002·The Journal of Continuing Education in the Health Professions·M Z Pelias
Mar 7, 2002·Epilepsia·J M PellockW D Shields

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Citations

Jul 2, 2008·Paediatric Drugs·Allison M Chung, Lea S Eiland
Jan 5, 2008·Journal of Child Neurology·Serdal GungorSaim Yologlu

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