Pediatric patients with intravascular devices: polymicrobial bloodstream infections and risk factors.

Journal of Pathogens
Wes OnlandWing-Yen Wong

Abstract

A retrospective study was conducted, including 61 patients with long-term intravascular devices (IVDs) admitted to the Childrens Hospital Los Angeles with diverse underlying diseases, different types of catheters, and culture-proven catheter-related bloodstream infections (BSIs). Within these patients, 125 catheter-related BSIs occurred, and the incidence of monomicrobial and polymicrobial BSIs was evaluated. Risk factors for polymicrobial BSIs were determined. Forty-two BSIs contained more than one pathogen. These polymicrobial BSIs were observed more often in younger patients (<4.1 years versus ≥4.1 years) and less in patients using venous implanted ports. No other associations were found between the occurrences of polymicrobial BSIs and underlying diseases, other types of catheters, host defense status, parenteral nutrition, recurrences, or catheter removal. Patients with long-term IVDs at a younger age have a higher risk of developing a polymicrobial BSI. Future prospective studies should address the issue of polymicrobial infection in IVDs in more detail.

References

Nov 1, 1988·American Journal of Diseases of Children·W A Bonadio
Nov 1, 1993·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D PittetR P Wenzel
Oct 3, 1999·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·C ViscoliS Binda
Apr 17, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·L A MermelUNKNOWN Society for Healthcare Epidemiology of America
Nov 27, 2001·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R HauptE Castagnola
Apr 23, 2002·Archives of Internal Medicine·Issam I Raad, Hend A Hanna
May 1, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Christopher J Crnich, Dennis G Maki
Apr 16, 2003·British Journal of Haematology·Elio CastagnolaClaudio Viscoli
Sep 4, 2004·Microbes and Infection·Philippe EggimannDidier Pittet
Jan 29, 2005·Annals of Oncology : Official Journal of the European Society for Medical Oncology·G FratinoR Haupt
Apr 29, 2005·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Rogier C J de JongeReinoud J B J Gemke
Jun 21, 2005·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Elio CastagnolaRiccardo Haupt
Jul 13, 2005·Pediatric Clinics of North America·Samir S ShahTheoklis E Zaoutis
Feb 3, 2006·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M NørgaardH T Sørensen
Oct 5, 2006·Archives of Pediatrics & Adolescent Medicine·Wes OnlandWing-Yen Wong
Jun 21, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kenneth V I RolstonAmar Safdar
Jan 10, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kevin J DownesSamir S Shah
Apr 10, 2008·The Pediatric Infectious Disease Journal·Deena SutterJudith Epstein

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Citations

Feb 5, 2015·Transplant Infectious Disease : an Official Journal of the Transplantation Society·S TrifilioJ Mehta
Oct 17, 2012·Antimicrobial Agents and Chemotherapy·Brian M PetersMairi C Noverr
Oct 23, 2018·BMJ Case Reports·Kenji IwaiMitsuru Kubota
Nov 17, 2017·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Sunil Kumar Garg, Pragya Garg

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