Pediatric pituitary adenomas.

Archives of Pathology & Laboratory Medicine
Christopher Webb, Richard A Prayson

Abstract

Pituitary adenomas are relatively rare occurrences in the pediatric population, and there are few studies documenting the profile of these tumors in this age group. To study the clinical and pathologic features of pediatric pituitary adenomas in conjunction with a review of the available literature. A retrospective clinicopathologic review of 20 pediatric patients (younger than 20 years of age) with pituitary adenomas resected during a 24.5-year period (1981-2005). A total of 20 patients, including 12 females and 8 males, comprise the study group. Mean age at onset of symptoms was 14.0 years (range, 5-18 years). Four patients had onset of symptoms before the age of 12 years. The majority of patients presented with headaches (n = 12), visual disturbances (n = 12) or, in females, menstrual dysfunction (n = 9/12). Tumor size based on radiographic data was known for 19 tumors; 12 adenomas were greater than 1 cm in greatest dimension, and 7 were less than 1 cm. On follow-up, 2 patients with total gross tumor resections had recurrent adenomas; time to recurrence was 5 months and 17 months, respectively. Nine adenomas stained solely for prolactin, 5 for adrenocorticotropic hormone, and 3 for growth hormone. Two stained for growth horm...Continue Reading

References

Aug 1, 1978·Journal of Neurosurgery·I L Richmond, C B Wilson
Feb 1, 1990·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·G Maira, C Anile
Jan 1, 1986·Acta Endocrinologica. Supplementum·S M Shalet
Jan 1, 1985·Pediatric Neuroscience·S L KanterA L Rhoton
Oct 1, 1983·Journal of Neurosurgery·B FraioliP Celli
Jan 1, 1981·Epidemiologic Reviews·E B Gold
Feb 1, 1995·Neurosurgery·T Mindermann, C B Wilson
Feb 1, 1994·Neurosurgery·E H DyerP Derome
Feb 1, 1994·Journal of Neurosurgery·M D PartingtonB W Scheithauer
Dec 22, 1999·The Journal of Clinical Endocrinology and Metabolism·S Kunwar, C B Wilson
Mar 27, 2001·Journal of Endocrinological Investigation·E De MenisN Conte
Mar 8, 2005·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·P PandeyA K Mahapatra

❮ Previous
Next ❯

Citations

Apr 25, 2009·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·L Drori-HerishanuC A Stratakis
Jan 15, 2020·Hormones : International Journal of Endocrinology and Metabolism·Marta Araujo-CastroEider Pascual-Corrales
May 13, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Davide LocatelliNurperi Gazioglu
Jul 20, 2017·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Nannan ZhangShu Jiang
Sep 10, 2015·The Journal of Craniofacial Surgery·Rucai ZhanXingang Li
Apr 28, 2020·Laryngoscope Investigative Otolaryngology·Nyall R LondonPatrick C Walz
Aug 26, 2014·The Journal of Craniofacial Surgery·Zhi-hang ZhouXiu-wu Bian
Dec 24, 2008·Journal of Pediatric Health Care : Official Publication of National Association of Pediatric Nurse Associates & Practitioners·Patricia Ryan-Krause
Jul 29, 2010·Journal of Pediatric Endocrinology & Metabolism : JPEM·Paravee KatavetinLynne L Levitsky
Jan 27, 2011·Pediatric Radiology·Jason W Schroeder, L Gilbert Vezina

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

JAMA : the Journal of the American Medical Association
M Berant, P Lanzkowsky
Zeitschrift für Tuberkulose
B KATTENTIDT
Actas urologicas españolas
J L Nogueira March
© 2021 Meta ULC. All rights reserved