Pediatric rheumatic disease in the intensive care unit: lessons learned from 15 years of experience in a tertiary care pediatric hospital

Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Suhas M RadhakrishnaBracha Shaham

Abstract

This study describes the 15-yr experience of a large urban tertiary care children's hospital in treating critically ill patients with pediatric rheumatic diseases. Retrospective case series. Children's Hospital Los Angeles, a large urban tertiary care children's hospital. All patients with pediatric rheumatic diseases admitted to the Children's Hospital Los Angeles pediatric intensive care unit from January 1995 to July 2009. None. An internal database and medical records were reviewed for demographics, diagnoses, treatments, organ dysfunction, interventions, infections, and outcomes. Standardized mortality ratio was calculated based on Pediatric Risk of Mortality III estimated mortality. Factors associated with mortality were identified by univariate analyses.Ninety patients with 122 total admissions were identified. The majority of patients were Hispanic (63%), female (73%), and had systemic lupus erythematosus (62%). Pediatric rheumatic disease-related complications (50%) were the most common reason for admission; 32% of admissions involved multiorgan dysfunction. Eighteen admissions (15%) resulted in mortality. Deaths were most commonly attributed to combined infection and active rheumatic disease (50%), infection only (22%...Continue Reading

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Oct 16, 2008·The American Journal of the Medical Sciences·Fernando HolguinJesse Roman
Oct 17, 2009·The Journal of Rheumatology·Linda T HirakiEarl D Silverman

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Citations

Feb 28, 2013·Current Rheumatology Reports·Rhina D CastilloKatherine A B Marzan
Sep 21, 2016·Emerging Infectious Diseases·Mario AbinunHelen E Foster
Sep 25, 2020·Journal of Intensive Care Medicine·Malini MahendraMartina A Steurer

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