Pediatric stroke associated with new onset type 1 diabetes mellitus: case reports and review of the literature

Pediatric Diabetes
Josephine HoDanièle Pacaud

Abstract

Neurological deterioration in children with diabetic ketoacidosis (DKA) is commonly caused by cerebral edema. However, stroke should also be suspected when focal neurological deficits are apparent, because children with hyperglycemia and DKA are prone to thrombosis. We report three cases of pediatric stroke associated with new onset type 1 diabetes mellitus (T1DM). The first case presented with sinovenous thrombosis, and the other two cases presented in DKA and had a late diagnosis of ischemic stroke following neurological deterioration. Our recent experiences and review of the literature emphasize the importance of early diagnosis, investigation, and treatment for patients that present with new onset T1DM and stroke.

References

Jan 1, 1990·Diabetes Care·A L Rosenbloom
Feb 1, 1987·Critical Care Medicine·R K KanterM J Stuart
May 18, 1974·Lancet·W R TimperleyJ D Ward
Jun 29, 1974·Lancet·J M AndersonD Thistlethwaite
Aug 3, 1974·British Medical Journal·F E PrestonJ D Ward
Jul 21, 1983·The New England Journal of Medicine·D W Foster, J D McGarry
Apr 1, 1981·The Journal of Pediatrics·S C Duck, E Kohler
May 1, 1981·Irish Journal of Medical Science·F ShanahanM I Drury
Mar 1, 1996·Journal of Diabetes and Its Complications·T F RoeM D Nelson
Sep 10, 1998·Stroke; a Journal of Cerebral Circulation·S SchwabW Hacke
Sep 28, 2000·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·C CognardJ Moret
Dec 29, 2000·Seminars in Thrombosis and Hemostasis·T K Nordt, C Bode
Feb 15, 2001·The New England Journal of Medicine·N GlaserUNKNOWN Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics
Mar 10, 2001·Stroke; a Journal of Cerebral Circulation·A DoerflerM Forsting
Jun 23, 2001·Archives of Disease in Childhood·J A EdgeD B Dunger
Jan 29, 2002·Diabetes·Mikko J JärvisaloOlli T Raitakari
Feb 28, 2002·Archives of Disease in Childhood·S KeaneJ A Edge
Nov 5, 2002·Pediatrics·Lidia V GabisNicholas J Lenn
Dec 4, 2002·The Journal of Pediatrics·James P MarcinUNKNOWN American Academy of Pediatrics. The Pediatric Emergency Medicine Collaborative Research Commitee
Mar 1, 2003·Paediatric Drugs·Ulrike Nowak-GöttlFenella Kirkham
Apr 5, 2003·Stroke; a Journal of Cerebral Circulation·Harold P AdamsUNKNOWN Stroke Council of the American Stroke Association
Aug 19, 2003·Surgical Neurology·Der-Yang ChoHan-Chun Lee
Mar 16, 2004·Pediatric Diabetes·Mehmet Akif OzdemirYasemin Altuner Torun
Oct 14, 2004·The Journal of Pediatrics·Jody S KrantzFrancine R Kaufman
Feb 3, 2005·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Josephine HoJean K Mah

❮ Previous
Next ❯

Citations

Mar 23, 2011·Stroke Research and Treatment·Jennifer Ruth FosterDouglas D Fraser
Mar 19, 2013·The Journal of Pediatrics·Perrin C White, Bryan A Dickson
Jul 20, 2019·Journal of Pediatric Endocrinology & Metabolism : JPEM·Sonum A BharillCathrine Constantacos
Feb 6, 2015·Annals of Pediatric Endocrinology & Metabolism·Jeesuk Yu
Feb 9, 2013·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Thai Hoa TranAlik Kornecki
May 16, 2014·Journal of Pediatric Endocrinology & Metabolism : JPEM·Ayla GüvenBülent Tasel
Jan 29, 2014·Journal of Pediatric Endocrinology & Metabolism : JPEM·Nesibe AkyürekBeray Selver Eklioglu
Mar 22, 2013·Journal of Pediatric Endocrinology & Metabolism : JPEM·Zohreh ShoarGeoffrey Rezvani
Nov 28, 2007·Pediatrics·Farid H MahmudDouglas D Fraser

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.

Autoimmune Diabetes & Tolerance

Patients with type I diabetes lack insulin-producing beta cells due to the loss of immunological tolerance and autoimmune disease. Discover the latest research on targeting tolerance to prevent diabetes.