Pediatric thyroid surgery and management of thyroid nodules - an institutional experience over a 10-year period

International Journal of Pediatric Endocrinology
Wen JiangRon S Newfield

Abstract

We reviewed our institutional experience in the diagnosis and management of pediatric thyroid nodules and well-differentiated thyroid carcinoma (WDTC), highlighting the unique challenges in this population. IRB approved retrospective chart review was conducted on patients who underwent fine needle aspiration (FNA) or thyroid surgery from 1/1/2001 to 12/31/2010 at Rady Children's Hospital San Diego, a tertiary referral center in Southern California. Patients thus identified who completed their initial treatment at our institution were included. Total of 79 subjects qualified; 20 had FNA only, and 59 underwent thyroid surgery. Of the latter, 29 had benign histology and 30 had WDTC. Average age was 14.5 years with a female: male ratio of 4:1 for WDTC versus 1.6:1 for benign nodules. When compared to final pathology, malignancy rate was high in indeterminate FNA cytology at 60 %. Neck metastasis was noted in 40 % and pulmonary spread in 10 % of patients. There was a 2.75 fold increase in malignant cases (n = 22) treated during 2006-2010 compared to 2001-2005 (n = 8) with more advanced disease at initial presentation. Ninety percent of WDTC patients received adjuvant I-131 treatment with an initial average dose of 132.4 mCi. Despite...Continue Reading

References

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Citations

Jul 3, 2016·International Journal of Pediatric Otorhinolaryngology·Jason TrahanAnita Jeyakumar
Aug 8, 2020·Annals of Saudi Medicine·Osama Ibrahim AlmosallamSaud AlShanafey
Mar 28, 2021·European Journal of Pediatrics·Emine Ayça CimbekGülay Karagüzel

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BETA
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