Pediatric thyroidectomy in a high volume thyroid surgery center: Risk factors for postoperative hypocalcemia

Journal of Pediatric Surgery
Yufei ChenAntonia E Stephen

Abstract

Hypocalcemia is a common complication following thyroid surgery. We seek to report on our experience in pediatric thyroidectomy in a high volume thyroid surgery center and accurately assess the incidence of postoperative hypocalcemia. A retrospective review of patients aged 18 and younger who underwent thyroid surgery between 1992 and 2013. The primary endpoints were the occurrence of postoperative hypocalcemia as by defined as a nadir calcium <8.0mg/dL and being discharged on oral calcium supplementation, need for intravenous calcium and the occurrence of permanent hypoparathyroidism. 171 patients who underwent 186 thyroid operations were analyzed. The average age was 15.4years with 82.3% female. The most common indications for surgery were nodular disease (74.7%) and hyperthyroidism (12.4%). 24 patients (12.9%) experienced postoperative hypocalcemia with 13 (7.0%) requiring intravenous calcium infusion. One patient (0.9%) experienced permanent hypoparathyroidism. Risk factors for postoperative hypocalcemia included total thyroidectomy (OR 7.39, p<0.01), central and bilateral lateral neck dissection (OR 22.26, p=0.01), Graves' disease (OR 3.99, p=0.02), and malignancy (OR 2.96, p=0.03). Pediatric patients who undergo total thy...Continue Reading

References

Jan 1, 1997·The British Journal of Surgery·A C See, K C Soo
Jul 31, 1998·American Journal of Surgery·R BergamaschiJ P Arnaud
Mar 20, 2001·Archives of Otolaryngology--head & Neck Surgery·A R SassonJ A Ridge
Apr 3, 2002·Archives of Otolaryngology--head & Neck Surgery·Neil Bhattacharyya, Marvin P Fried
Jul 21, 2005·Thyroid : Official Journal of the American Thyroid Association·Geeta LalOrlo H Clark
Jun 5, 2008·The Journal of Clinical Endocrinology and Metabolism·Julie Ann SosaSanziana A Roman
Mar 25, 2009·Archives of Internal Medicine·Adit A GindeCarlos A Camargo
Jul 7, 2009·The Journal of Surgical Research·Anna E BargrenHerbert Chen
Jul 29, 2009·Journal of Pediatric Surgery·Mehul V RavalMarleta Reynolds
Oct 19, 2010·Thyroid : Official Journal of the American Thyroid Association·Catherine E PesceMartha A Zeiger
Dec 15, 2010·World Journal of Surgery·James Kirkby-BottFausto Palazzo
Dec 22, 2010·Archives of Otolaryngology--head & Neck Surgery·Christine G GourinRobert E Bristow
May 28, 2011·Journal of Pediatric Surgery·James H WoodRobert C McIntyre
Jun 8, 2011·The Journal of Clinical Endocrinology and Metabolism·Michael F HolickUNKNOWN Endocrine Society
Jul 17, 2012·The Journal of Surgical Research·Jocelyn F BurkeHerbert Chen
Jul 19, 2012·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Rishi VashishtaRahul K Shah
Dec 13, 2012·American Journal of Surgery·Yihan LinRobert C McIntyre
Jun 19, 2013·Indian Journal of Endocrinology and Metabolism·C Gopalakrishnan NairPradeep Jacob
Nov 8, 2013·Journal of Pediatric Endocrinology & Metabolism : JPEM·Oksana LazarevaElka Jacobson-Dickman
Jan 10, 2014·The British Journal of Surgery·O EdafeS P Balasubramanian
Mar 1, 2014·JAMA Otolaryngology-- Head & Neck Surgery·Tomas P GriffinPatrick Sheahan

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Citations

Jan 24, 2018·Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'oto-rhino-laryngologie Et De Chirurgie Cervico-faciale·Fabio MedasPietro Giorgio Calò
Nov 18, 2015·Current Opinion in Oncology·Elisabeth T Tracy, Sanziana A Roman
Aug 24, 2017·OTO Open : the Official Open Access Journal of the American Academy of Otolaryngology--Head and Neck Surgery Foundation·Paul D JudgeWilliam Lydiatt
Jul 31, 2018·Expert Review of Endocrinology & Metabolism·Agathoklis KonstantinidisSanziana A Roman
Aug 8, 2020·Annals of Saudi Medicine·Osama Ibrahim AlmosallamSaud AlShanafey
Oct 8, 2020·Journal of Pediatric Endocrinology & Metabolism : JPEM·Rob GonsalvesOliver J Oatman
Oct 21, 2020·World Journal of Surgery·John K ThomasDeepak Thomas Abraham
Oct 3, 2020·Journal of Pediatric Surgery·Ankitha RadakrishnanMehul V Raval
Mar 7, 2020·American Journal of Otolaryngology·Sina J TorabiYan Lee
Mar 12, 2021·International Journal of Pediatric Otorhinolaryngology·Kung-Ting KaoJean-Pierre Chanoine
Mar 13, 2021·Surgical Oncology Clinics of North America·Emily Christison-Lagay, Reto M Baertschiger
Jun 24, 2020·Seminars in Pediatric Surgery·Michael J Zobel, Benjamin E Padilla
Jul 18, 2021·Endocrinología, Diabetes Y Nutrición·Emilio García-GarcíaRosa Cabello-Laureano
Jul 25, 2021·Journal of Pediatric Surgery·David E WessonMonica E Lopez
Oct 15, 2021·JAMA Otolaryngology-- Head & Neck Surgery·Lourdes Quintanilla-DieckKen Kazahaya

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