Pedigree-based estimation of covariance between dominance deviations and additive genetic effects in closed rabbit lines considering inbreeding and using a computationally simpler equivalent model

Journal of Animal Breeding and Genetics = Zeitschrift Für Tierzüchtung Und Züchtungsbiologie
E N FernándezM Baselga

Abstract

Inbreeding generates covariances between additive and dominance effects (breeding values and dominance deviations). In this work, we developed and applied models for estimation of dominance and additive genetic variances and their covariance, a model that we call "full dominance," from pedigree and phenotypic data. Estimates with this model such as presented here are very scarce both in livestock and in wild genetics. First, we estimated pedigree-based condensed probabilities of identity using recursion. Second, we developed an equivalent linear model in which variance components can be estimated using closed-form algorithms such as REML or Gibbs sampling and existing software. Third, we present a new method to refer the estimated variance components to meaningful parameters in a particular population, i.e., final partially inbred generations as opposed to outbred base populations. We applied these developments to three closed rabbit lines (A, V and H) selected for number of weaned at the Polytechnic University of Valencia. Pedigree and phenotypes are complete and span 43, 39 and 14 generations, respectively. Estimates of broad-sense heritability are 0.07, 0.07 and 0.05 at the base versus 0.07, 0.07 and 0.09 in the final genera...Continue Reading

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Citations

Jan 28, 2018·Genetics, Selection, Evolution : GSE·Luis VaronaZulma G Vitezica
Sep 29, 2019·Genetics, Selection, Evolution : GSE·David González-DiéguezZulma G Vitezica
Jul 8, 2017·Journal of Animal Breeding and Genetics = Zeitschrift Für Tierzüchtung Und Züchtungsbiologie·E N FernándezM Baselga
Jan 9, 2020·Journal of Animal Breeding and Genetics = Zeitschrift Für Tierzüchtung Und Züchtungsbiologie·Kristen AlvesFlavio S Schenkel
Aug 21, 2020·Genetics, Selection, Evolution : GSE·Tom Druet, Andres Legarra
Mar 22, 2018·Frontiers in Genetics·Luis VaronaZulma G Vitezica
Mar 15, 2019·Journal of Animal Science·Joaquim CasellasJose L Noguera
May 11, 2018·Genetics·Tao XiangAndres Legarra
Jan 20, 2021·Genetics, Selection, Evolution : GSE·Luis Gomez-RayaJack C M Dekkers

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