PEDOT-CNT Composite Microelectrodes for Recording and Electrostimulation Applications: Fabrication, Morphology, and Electrical Properties.

Frontiers in Neuroengineering
Ramona GerwigMartin Stelzle

Abstract

Composites of carbon nanotubes and poly(3,4-ethylenedioxythiophene, PEDOT) and layers of PEDOT are deposited onto microelectrodes by electropolymerization of ethylenedioxythiophene in the presence of a suspension of carbon nanotubes and polystyrene sulfonate. Analysis by FIB and SEM demonstrates that CNT-PEDOT composites exhibit a porous morphology whereas PEDOT layers are more compact. Accordingly, capacitance and charge injection capacity of the composite material exceed those of pure PEDOT layers. In vitro cell culture experiments reveal excellent biocompatibility and adhesion of both PEDOT and PEDOT-CNT electrodes. Signals recorded from heart muscle cells demonstrate the high S/N ratio achievable with these electrodes. Long-term pulsing experiments confirm stability of charge injection capacity. In conclusion, a robust fabrication procedure for composite PEDOT-CNT electrodes is demonstrated and results show that these electrodes are well suited for stimulation and recording in cardiac and neurophysiological research.

Citations

Aug 1, 1969·Electroencephalography and Clinical Neurophysiology·R Spehlmann
Oct 17, 2015·Biosensors·Nicolas A AlbaX Tracy Cui
Mar 27, 2015·Neuromodulation : Journal of the International Neuromodulation Society·Himadri Shekhar MandalTheodore Constantine Dumas
Jun 19, 2015·IEEE Transactions on Bio-medical Engineering·Takashi D Y KozaiXinyan Tracy Cui
Apr 12, 2016·Frontiers in Neuroscience·Peter D Jones, Martin Stelzle
Apr 10, 2015·Neuron·Jae-Woong JeongJohn A Rogers
May 6, 2014·Frontiers in Neuroengineering·Elisa CastagnolaLuciano Fadiga
Jun 9, 2016·Biosensors & Bioelectronics·I Mitch TaylorXinyan Tracy Cui
Mar 24, 2016·IEEE Transactions on Bio-medical Engineering·Chet T MoritzRajesh P N Rao
Mar 10, 2017·Science Advances·Liangqi OuyangDavid C Martin
Sep 14, 2017·Advanced Materials·Kostas KostarelosJose A Garrido
Feb 26, 2019·Advanced Materials·Kezhong WangGordon Wallace
May 14, 2016·Scientific Reports·Lilach BareketYael Hanein
Nov 11, 2014·Beilstein Journal of Nanotechnology·Antonina M Monaco, Michele Giugliano
Aug 15, 2018·International Journal of Molecular Sciences·Krishna FeronPaul C Dastoor
Sep 7, 2019·Advanced Healthcare Materials·Stefano CarliFabio Biscarini
Nov 1, 2017·Advanced Biosystems·Günther ZeckRoland Thewes
Jul 14, 2016·Micromachines·Nikolas GaioRonald Dekker
Jan 2, 2017·Microsystems & Nanoengineering·John P SeymourEuisik Yoon
Aug 7, 2015·Bioengineering·Himadri S MandalJoseph J Pancrazio
Jun 9, 2020·Frontiers in Neuroscience·Peter D JonesMichele Giugliano
Nov 19, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ariana Villarroel MarquezAmir Pakdel
Feb 2, 2021·Frontiers in Bioengineering and Biotechnology·Mohaddeseh VafaieePezhman Sasanpour
Jun 4, 2020·Journal of Electroanalytical Chemistry·Tran N H NguyenHyowon Lee

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