Pelvic organ dysfunction is more prevalent and severe in MSA-P compared to Parkinson's disease

Neurourology and Urodynamics
Tatsuya YamamotoSatoshi Kuwabara

Abstract

It is usually difficult to distinguish between idiopathic Parkinson's disease (PD) and parkinsonian-type multiple system atrophy (MSA-P) in the early stage. However, it is important to make a careful early-stage diagnosis. Therefore, we determined whether an examination of pelvic organ dysfunction would be helpful to distinguish between PD and MSA-P. We recruited 61 patients with PD and 54 patients with MSA-P who were examined at our neurology clinic. The mean ages of the patients with PD and MSA-P were 67 and 64 years, respectively. The mean disease duration of both groups was 3.2 years. We administered a questionnaire on pelvic organ dysfunction to the PD and MSA-P groups. The questionnaire had sections focusing on bladder, bowel, and sexual function. Dysfunction, as described in the responses, was evaluated as normal, mild (>once a month), moderate (>once a week), or severe (>once a day). The Mann-Whitney U-test was used for statistical analysis. Compared with the PD group, the prevalence and severity of pelvic dysfunction in the MSA-P group was significantly higher for urinary urgency (MSA-P 76%, PD 58%, P<0.05), retardation in initiating urination (79%, 48%, P<0.05), prolongation in urination (79%, 72%, P<0.05), and consti...Continue Reading

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Citations

Feb 25, 2017·Journal of Parkinson's Disease·Phillip A EngenAli Keshavarzian
Apr 11, 2012·Neurourology and Urodynamics·Kristian Winge, Kurt K Nielsen
Oct 20, 2012·Movement Disorders : Official Journal of the Movement Disorder Society·Keiichiro TerayamaTatsuya Yamamoto
Jun 12, 2013·Neurourology and Urodynamics·Tatsuya YamamotoSatoshi Kuwabara
Dec 6, 2018·Movement Disorders Clinical Practice·Anne Pavy-Le TraonUNKNOWN Members of the MDS Committee on Rating Scales Development
Feb 13, 2017·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Jinhua ZhengYanming Xu
Nov 11, 2017·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Ryuji SakakibaraTomonori Yamanishi
Jul 3, 2019·Frontiers in Neuroscience·Holly Ann Roy, Alexander L Green
Jul 14, 2021·Expert Review of Neurotherapeutics·Luca MarsiliCarlo Colosimo

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