Pelvic perfusion hyperthermia for advanced pelvic malignancies

The Japanese Journal of Surgery
I YokoyamaT Kondo


Pelvic perfusion hyperthermia (PPH) for malignant gynecologic diseases in the pelvis was performed for four hours with favorable results. Serial monitoring of chemotherapeutic drug concentrations in the blood, tissues and circuit showed that the drugs were satisfactorily incorporated into the tumor bearing area and that the systemic leak was minimal with no demonstrable systemic side effects. The temperature of the tumor was kept between 41.8 degrees C and 42.7 degrees C for over three hours. The esophageal temperature was maintained below 40 degrees C throughout the procedure. In one patient, there was an eighty percent reduction in tumor size and in the other, a complete regression of the tumor. We conclude that the PPH is a procedure that warrants further attention as an adjunct to cancer therapy for malignant pelvic tumors.


Aug 30, 2008·Surgical Oncology Clinics of North America·Giovanni BegossiHarold J Wanebo

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.