PMID: 8976699Oct 1, 1996Paper

Penetrating keratoplasty in Africa: graft survival and visual outcome

The British Journal of Ophthalmology
D YorstonA Foster

Abstract

To study the survival and visual outcome of penetrating keratoplasty in an African setting. A retrospective analysis of 216 corneal grafts, performed on 203 eyes of 186 patients, at Kikuyu Hospital, Kenya over a 5 year period. Half of the transplants were carried out for keratoconus with only 5% of the grafts being undertaken for corneal scarring caused by trachoma or measles. The average follow up was 27.3 months. The probability of graft survival at 2 years was 87.4% (95% CI 80.6%-94.3%) for keratoconus and 64.7% (95% CI 54.8%-74.6%) for other corneal pathologies. Forty seven grafts (21.8%) in 36 patients (17.7%) are known to have become opaque. The commonest causes of graft opacification were bacterial keratitis (6.0%), endothelial failure (6.0%), and graft rejection (5.1%). Preoperatively 55% of keratoconus eyes and 75.7% of non-keratoconus eyes were blind. Postoperatively, 5% of keratoconus eyes and 41.7% of the non-keratoconus eyes were blind. Normal vision was achieved in 53.7% of operated eyes. Grafts carried out for keratoconus had a better visual outcome than grafts performed for other corneal pathologies. Preoperatively, 12.4% of keratoconus and 48.5% of non-keratoconus patients were blind in their better eye. Postop...Continue Reading

References

Oct 1, 1992·The British Journal of Ophthalmology·D Yorston, A Foster
Jul 1, 1992·Transactions of the Royal Society of Tropical Medicine and Hygiene·A Foster, D Yorston
Jan 1, 1991·Documenta Ophthalmologica. Advances in Ophthalmology·J S StilmaP Hardus
Jan 1, 1990·Eye·C M KirknessN S Rice
Jan 1, 1990·Eye·C M KirknessA D Steele
Jan 1, 1990·Eye·A K BatesN S Rice
Dec 1, 1989·Archives of Ophthalmology·H R TaylorP A Rapoza
Feb 1, 1989·The British Journal of Ophthalmology·H FaalA Foster
Jun 15, 1984·Documenta Ophthalmologica. Advances in Ophthalmology·E Wagner
Jun 1, 1982·Ophthalmology·P G PaglenR G Webster

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Citations

Dec 6, 2002·Ophthalmology·David B YorstonClare Gilbert
Mar 15, 2001·Cornea·M SitA R Slomovic
Jun 27, 2003·Cornea·Daniel J WeisbrodAllan R Slomovic
Jan 25, 2008·Cornea·Abdullah Al-FawazUNKNOWN King Khaled Eye Specialist Hospital Corneal Transplant Study Group
Feb 9, 2012·Cornea·Yee Onn KokSeng Chee Loon
Jan 10, 1998·The British Journal of Ophthalmology·L DandonaG N Rao
Apr 27, 1999·The British Journal of Ophthalmology·R J BowmanC M Kirkness
Jan 25, 2003·The British Journal of Ophthalmology·R Dandona, L Dandona
Nov 27, 2009·American Journal of Ophthalmology·Jared D AmentClaes H Dohlman
May 18, 2011·Clinical & Experimental Ophthalmology·Qing PanYangshun Gu
Oct 3, 2015·The Review of Scientific Instruments·Xun Jie Jeesmond HongT Aung
Jan 31, 2012·Survey of Ophthalmology·Saul N RajakMatthew J Burton
Aug 24, 2017·International Ophthalmology·Otavio A MagalhaesRaissa C Ferreira
Sep 6, 2007·International Ophthalmology·Samar A Al-Swailem
Jun 1, 2000·Cornea·S C BrierlyM J Mannis
Apr 17, 2021·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Prince Kwaku AkowuahStephen Ankamah-Lomotey
Aug 26, 2021·Retina·Rodrigo AnguitaDavid G Charteris

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