Penetrating keratoplasty in the mentally retarded

Eye
A M McElvanney, H P Adhikary

Abstract

Penetrating keratoplasty is infrequently performed in the mentally retarded due to the high risk of serious post-operative complications, in particular wound rupture and severe inflammation of the graft. Graft survival is hindered by the patient's tendency for eye rubbing and possibly self-inflicted injury. Adequate nursing support is essential to ensure strict compliance with post-operative treatment. A retrospective study of corneal graft outcomes in mentally retarded patients was undertaken to assess graft survival, visual rehabilitation, post-operative complications and the influence on social behaviour. Six cases of penetrating keratoplasty performed in mentally retarded patients by one surgeon are presented. A continuous 10-0 nylon suture was employed in all cases. In 2 cases surgery was undertaken following perforation of the globe in patients with Down's syndrome. The grafts were retained in all cases and 2 patients achieved reasonably good acuity, although formal visual acuity assessment in these patients is limited. Penetrating keratoplasty in mentally retarded patients is a potentially hazardous procedure and patients require close supervision and good support care. This series demonstrates that relatively successful...Continue Reading

References

Jul 11, 1975·American Journal of Ophthalmology·P S BinderH E Kaufman
Feb 1, 1992·Acta Ophthalmologica·O H Haugen
Mar 1, 1991·The British Journal of Ophthalmology·K W Sharif, T A Casey
Feb 15, 1990·American Journal of Ophthalmology·J M FrantzH E Kaufman
Aug 1, 1988·Acta Ophthalmologica·L Jacobson
Dec 1, 1968·American Journal of Ophthalmology·M M SlusherR D Mulberger
Jan 1, 1971·The British Journal of Ophthalmology·D Pierse, P Eustace
Oct 1, 1994·Ophthalmology·S J TuftR J Buckley
Jun 1, 1963·The British Journal of Ophthalmology·J F CULLEN

❮ Previous
Next ❯

Citations

Mar 29, 2000·Journal of Chromatography. a·B Tenberken-PötzschH W Gäggeler
Sep 25, 2008·Cornea·Gerardo P García García, José Belmonte Martínez
Jun 26, 2001·The British Journal of Ophthalmology·A G CoombesC K Rostron
Dec 19, 2002·The British Journal of Ophthalmology·J StoiberG Grabner
Jan 10, 2002·Acta Ophthalmologica Scandinavica·O H HaugenT Bertelsen
Jun 17, 2015·Survey of Ophthalmology·Jack S ParkerGerrit R J Melles
May 10, 2005·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·M Patricia CastanedaJoseph T Flynn
Nov 5, 2013·Cornea·Barbara KollerIrmingard M Neuhann

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.