PMID: 1202684May 1, 1975Paper

Penetration of anti-lysosome serum in macrophages and the localization of anti-lysosome antibodies in their structures

Tsitologiia
Kh M Isina, M Ia Korn

Abstract

Penetration of antilysosomal sera into living macrophages, their localization on subcellular structures, and their effects upon the cell, were studied by means of immunofluorescence technique. The rabbit antilysosomal (antimembrane) immune globulins were found to be ingested by the mouse macrophages and to exert obvious effect upon the macrophage function. The specificity of used antisera was confirmed by findings obtained with fixed macrophages.

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