Penile carcinoma and HPV infection (Review)

Experimental and Therapeutic Medicine
Lucian IorgaOvidiu Gabriel Bratu

Abstract

Penile carcinoma is a relatively frequent health issue in the developing countries such as Africa, Asia and South America, usually affecting men aged between 50 and 70 years. It is a highly treatable disease in its early stages, but has serious physical and psychological consequences. Usually, penile carcinoma is located in the penile glans, in approximately half the cases, with the most frequent histological type being squamous cell carcinoma with its microscopic subtypes. A large number of risk factors have been reported for this disease, having a multifactorial etiology, HPV infection being one of the most important factors involved in its appearance. Out of the HPV DNA positive genital cancers HPV-16 is the most frequently found type in men, followed by HPV-18. The evolution of penile cancer includes two independent carcinogenic pathways, related or unrelated to HPV infection. There is limited data available in literature regarding HPV-related neoplasia, as well as on the efficacy of vaccination in men, with studies still ongoing.

References

Jul 30, 1992·International Journal of Cancer. Journal International Du Cancer·P J SnijdersJ M Walboomers
Feb 7, 2003·The New England Journal of Medicine·Nubia MuñozUNKNOWN International Agency for Research on Cancer Multicenter Cervical Cancer Study Group
Feb 10, 2004·The Journal of Infectious Diseases·Bethany A WeaverLaura A Koutsky
Mar 31, 2004·The Lancet Oncology·Sanjeev MisraNaresh C Misra
Jan 22, 2005·Critical Reviews in Oncology/hematology·Anna Maria MosconiChristine Theodore
Mar 30, 2006·International Journal of Cancer. Journal International Du Cancer·Anne P LontPeter J F Snijders
Jun 23, 2006·The New England Journal of Medicine·Rachel L WinerLaura A Koutsky
Sep 23, 2006·The Journal of Infectious Diseases·Eileen F DunneAnna R Giuliano
Sep 23, 2006·International Journal of Cancer. Journal International Du Cancer·Lalle HammarstedtEva Munck-Wikland
Jun 11, 2008·Canadian Urological Association Journal = Journal De L'Association Des Urologues Du Canada·Elantholi P SaibishkumarJoan Sweet
Nov 7, 2008·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Luciano A FavoritoSidney Glina
Dec 17, 2008·Cancer Causes & Control : CCC·Danielle M BackesJennifer S Smith
Mar 27, 2009·The New England Journal of Medicine·Aaron A R TobianRonald H Gray
Aug 27, 2009·Journal of Clinical Pathology·C Miralles-GuriS de Sanjosé
Jun 10, 2010·The New England Journal of Medicine·K Kian AngMaura L Gillison
Aug 19, 2010·Urology·Mariela R Pow-SangVictor Destefano
Aug 19, 2010·Urology·Alcides ChauxAntonio L Cubilla
Dec 15, 2010·The Journal of Infectious Diseases·Eftyhia VardasDalya Guris
Jan 26, 2011·The American Journal of Surgical Pathology·Antonio L CubillaFrancisco Xavier Bosch
Feb 4, 2011·The New England Journal of Medicine·Anna R GiulianoDalya Guris
Dec 14, 2011·Clinical and Vaccine Immunology : CVI·Richard J HillmanElizabeth I O Garner
Jan 13, 2012·The Journal of Infectious Diseases·Gabriella M AnicAnna R Giuliano
Mar 14, 2013·Clinical Oral Investigations·Camila Maria Beder RibeiroJair Carneiro Leao
Nov 19, 2013·Urologic Oncology·Amber FlahertyPhilippe E Spiess
Dec 19, 2013·Experimental and Therapeutic Medicine·Milin PengGuozhong Gong
May 14, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Eva Serup-HansenHanne Havsteen
Jun 5, 2014·Expert Opinion on Drug Discovery·Gautum AgarwalPhilippe E Spiess
Aug 26, 2014·The Journal of Urology·Rosa S DjajadiningratDaniëlle A M Heideman
Jan 24, 2015·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Thiago Costa do CoutoFelipe Dubourcq Barros
Jan 30, 2015·The Analyst·J CzepielA Wesełucha-Birczyńska
Dec 22, 2015·Papillomavirus Research·Anna R GiulianoEduardo Lazcano-Ponce
Jan 15, 2016·European Urology·Laia AlemanyUNKNOWN HPV VVAP study group

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Citations

Jul 3, 2021·Viruses·Kendal RosalikJasmine Han
Jan 14, 2022·Virchows Archiv : an International Journal of Pathology·Luca HladekRia Winkelmann

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