Pentasomy 8q in myelodysplasia

Cancer Genetics and Cytogenetics
Y L Kwong, T K Chan

Abstract

Trisomy 8 and, less commonly tetrasomy 8, are karyotypic aberrations found in myeloid malignancies. We describe a unique case of acute myeloid leukemia with partial pentasomy 8 resulting from duplication of isochromosome 8q, and discuss its possible roles in leukemogenesis.

References

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