Pentraxin3 and high-sensitive C-reactive protein are independent inflammatory markers released during high-intensity exercise.

European Journal of Applied Physiology
Toshiaki NakajimaRyozo Nagai

Abstract

High-intensity exercise shares similarities with acute phase responses of inflammatory diseases. We investigated the influences of acute exercise on inflammatory markers, plasma pentraxin3 (PTX3) and serum high-sensitive C-reactive protein (CRP) (hsCRP). Nine healthy male subjects (41 ± 3 years old) participated. Each subject performed three types of exercise; ergometer exercise at 70% workload of anaerobic threshold (AT) for 30 min (70% AT exercise), peak ergometer exercise (peak EX, 20 watt increase/min until fatigue) and resistance exercises of 70% 1 RM (70% RE) until exhaustion. We measured plasma PTX3, serum hsCRP, lactate, noradrenaline (NOR), white blood cells (WBC), interleukin-6 (IL-6) and myeloperoxidase (MPO), a marker of neutrophil degranulation. The effects of exercise on intracellular PTX3 and MPO in neutrophils were also investigated, by using flow cytometry analysis. Circulating PTX3 and hsCRP significantly increased immediately after 70% RE and peak EX, while they did not increase after 70% AT exercise. The exercise-induced fold increase in PTX3 and hsCRP relative to the resting level was positively correlated with the changes in WBC, NOR, lactate and MPO. The exercise-induced fold increase in IL-6 was positive...Continue Reading

References

Jan 1, 1992·European Journal of Applied Physiology and Occupational Physiology·D A McCarthyJ D Perry
Aug 1, 1994·Immunology Today·L Hoffman-Goetz, B K Pedersen
Jan 1, 1997·European Journal of Applied Physiology and Occupational Physiology·L M CastellE A Newsholme
Jul 6, 2000·European Journal of Applied Physiology·L L SmithD Holbert
Jul 14, 2000·Physiological Reviews·B K Pedersen, L Hoffman-Goetz
Feb 24, 2001·European Journal of Applied Physiology·K OstrowskiB K Pedersen
Jul 31, 2001·British Journal of Sports Medicine·R J Shephard
Sep 5, 2001·Molecular Immunology·J E Volanakis
Apr 19, 2002·Journal of Applied Physiology·Mutsuo YamadaKazuo Sugawara
May 20, 2003·São Paulo Medical Journal = Revista Paulista De Medicina·Valéria Maria NataleRoy Jesse Shephard
Jun 13, 2003·Journal of Sports Sciences·E FehrenbachH Northoff
Jun 19, 2003·The Journal of Clinical Investigation·Mark B Pepys, Gideon M Hirschfield
Dec 4, 2003·Medicine and Science in Sports and Exercise·Tracey PhillipsChristiaan Leeuwenburgh
Dec 12, 2003·BMC Physiology·Bjørn Audun RisøyHaakon B Benestad
Oct 13, 2004·Circulation·Roberto LatiniUNKNOWN Lipid Assessment Trial Italian Network (LATIN) Investigators
Mar 18, 2005·Journal of Applied Physiology·Anne Marie W Petersen, Bente Klarlund Pedersen
May 5, 2005·Medicine and Science in Sports and Exercise·Jonathan M PeakeJeff S Coombes
May 17, 2005·Journal of the American College of Cardiology·Christos Kasapis, Paul D Thompson
Sep 30, 2005·The American Journal of Pathology·Huijun SunJianglin Fan
Dec 17, 2005·Journal of Applied Physiology·Frank ZaldivarDan M Cooper
May 2, 2006·Sports Medicine·Eric P Plaisance, Peter W Grandjean
Sep 1, 2006·International Journal of Sports Medicine·F C MoorenW Nacken
Sep 23, 2006·Journal of Applied Physiology·Petra BüttnerFrank C Mooren
Nov 11, 2006·Arteriosclerosis, Thrombosis, and Vascular Biology·Kenji InoueTatsuhiko Kodama
Mar 29, 2007·The Journal of Experimental Medicine·Sébastien JaillonAlberto Mantovani
May 10, 2007·Scandinavian Cardiovascular Journal : SCJ·Pavel KunesJan Krejsek
May 15, 2007·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Michael BoehmeRalf Schindler
Jul 21, 2007·Atherosclerosis·Norihiko KotookaKoichi Node
Sep 1, 2007·Journal of Cellular and Molecular Medicine·Marco PrestaMarco Rusnati
Sep 11, 2007·Journal of Clinical Immunology·Alberto MantovaniBarbara Bottazzi

❮ Previous
Next ❯

Citations

Jan 8, 2013·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Christina TsitsimpikouAthanasios Jamurtas
Jul 13, 2012·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Asako MiyakiRyuichi Ajisaka
Feb 21, 2014·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Chun-Jung HuangEdmund O Acevedo
Jun 11, 2015·Scandinavian Journal of Medicine & Science in Sports·M van de VyverK H Myburgh
Jun 13, 2012·Clinica Chimica Acta; International Journal of Clinical Chemistry·Sang Hui ChuJustin Y Jeon
Dec 4, 2014·Metabolism: Clinical and Experimental·Aaron L SlusherChun-Jung Huang
Sep 15, 2011·European Journal of Preventive Cardiology·Taira FukudaToshiaki Nakajima
Dec 1, 2017·Sports Medicine - Open·Paula Andréa Malveira CavalcanteRonaldo Carvalho Araújo
May 9, 2018·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Aaron L SlusherChun-Jung Huang
Nov 8, 2018·Clinical Science·Yuki SatoTakuya Watanabe
Jul 11, 2018·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Asako Zempo-MiyakiSeiji Maeda
Jul 3, 2019·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Ting WuNanfang Li
Jun 25, 2020·International Journal of Molecular Sciences·Salvatore Santo SignorelliDomenico Di Raimondo
May 12, 2018·European Journal of Applied Physiology·Aaron L SlusherEdmund O Acevedo
Nov 1, 2017·Porto Biomedical Journal·Rita FerreiraDaniel Moreira-Gonçalves
Oct 13, 2018·Nutrients·Stefania OrrùAnnamaria Mancini

❮ Previous
Next ❯

Related Concepts

Related Feeds

Biomechanics

Biomechanics examines the generation of internal forces within the body and investigates the effects and control of forces that act on or are produced on tissues. Here are the latest discoveries.

Related Papers

The American Journal of Emergency Medicine
Geertje ThuijlsErik Heineman
Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition
Leo Galland
The Journal of Physiology
Ole Hartvig MortensenBente K Pedersen
Kidney International
Ernst MalleHermann-Josef Grone
© 2021 Meta ULC. All rights reserved