Peptic ulcer haemorrhage in Tartu County, Estonia: epidemiology and mortality risk factors

Scandinavian Journal of Gastroenterology
J SoplepmannM Juhola

Abstract

The aim of the study was to assess the epidemiology and mortality risk factors of peptic ulcer haemorrhage (PUH) in Tartu County, Estonia. In a prospective unselected defined area study, data for 144 patients aged > or = 15 years with new cases of PUH were analysed during a 2-year period. The incidence of PUH was 57 per 100,000 adult population per year, increasing from 12 in patients aged 20-29 years to more than 135 in those > or = 70 years. The incidence was 2.3-fold higher for men. The incidence of gastric ulcer haemorrhage was 26 (men, 33; women, 20) and that of duodenal ulcer 22 (men, 39; women, 9). Of the women 72% and of the men 37% were > or = 60 years. Nonsteroidal anti-inflammatory drugs (NSAIDs) were used by 45% of the patients (64% of women, 36% of men). Helicobacter pylori infection was present in 93% of the duodenal ulcer patients and in 81% of the gastric ulcer patients. Mortality (8%) was related to age, shock, haemoglobin < 80 g/l, cardiac comorbidity, and recurrence of haemorrhage. The incidence of PUH is relatively high owing to a high incidence among the younger population in Tartu County. Women with PUH are older, have consumed more NSAIDs, and have mainly gastric ulcer; men are younger, have consumed less...Continue Reading

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Citations

Jan 11, 2012·Nature Reviews. Gastroenterology & Hepatology·Marc BardouAlan N Barkun
Mar 14, 2001·Journal of Clinical Gastroenterology·R PellicanoA Ponzetto
Jun 1, 2011·Pharmacoepidemiology and Drug Safety·Kueiyu Joshua LinSonia Hernández-Díaz
Sep 17, 2005·Scandinavian Journal of Gastroenterology·Christian OhmannChristian Reinhold
Jul 5, 2015·Gastrointestinal Endoscopy Clinics of North America·Kyle J FortinskyAlan N Barkun
Jan 1, 2012·Clinical Medicine Insights. Gastroenterology·Christo J van Rensburg, Susan Cheer
Feb 10, 2011·The American Journal of Gastroenterology·Jordi Sánchez-DelgadoXavier Calvet
Feb 6, 2013·The American Journal of Gastroenterology·Grigorios I LeontiadisColin W Howden
Mar 24, 2012·European Journal of Gastroenterology & Hepatology·SeungJin BaeKi-Nam Shim
Jun 11, 2009·Alimentary Pharmacology & Therapeutics·J SadicG Lindell

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