Peptide-amphiphile nanofibers: a versatile scaffold for the preparation of self-assembling materials

Proceedings of the National Academy of Sciences of the United States of America
Jeffrey D HartgerinkSamuel I Stupp

Abstract

Twelve derivatives of peptide-amphiphile molecules, designed to self-assemble into nanofibers, are described. The scope of amino acid selection and alkyl tail modification in the peptide-amphiphile molecules are investigated, yielding nanofibers varying in morphology, surface chemistry, and potential bioactivity. The results demonstrate the chemically versatile nature of this supramolecular system and its high potential for manufacturing nanomaterials. In addition, three different modes of self-assembly resulting in nanofibers are described, including pH control, divalent ion induction, and concentration.

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Citations

Feb 3, 2011·Applied Microbiology and Biotechnology·Gundula A NollDirk Prüfer
Jun 10, 2008·World Journal of Urology·Daniel A HarringtonEarl Y Cheng
Mar 10, 2006·Annals of Biomedical Engineering·James J Norman, Tejal A Desai
Sep 17, 2009·Journal of Materials Science. Materials in Medicine·Jian-Zheng WangYing-Li Teng
Jan 16, 2007·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Yongchao WuXiaodong Guo
Apr 22, 2010·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Bin WuZhenwei Zou
May 17, 2006·Acta Biomaterialia·Elia BeniashSamuel I Stupp
May 12, 2005·Biomaterials·Narayan BhattaraiMiqin Zhang
Nov 24, 2004·Colloids and Surfaces. B, Biointerfaces·L A Smith, P X Ma
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Nov 14, 2008·Chemical Reviews·Liam C PalmerSamuel I Stupp
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Dec 19, 2007·Journal of the American Chemical Society·Matthew R DreherAshutosh Chilkoti
Mar 5, 2008·Journal of the American Chemical Society·Lorraine HsuSamuel I Stupp
Apr 22, 2010·Journal of the American Chemical Society·Charles J Bowerman, Bradley L Nilsson
Aug 6, 2011·Journal of the American Chemical Society·William C PomerantzSamuel H Gellman
Feb 13, 2008·Journal of the American Chemical Society·Steve R BullSamuel I Stupp
Apr 1, 2009·Journal of the American Chemical Society·Harunobu KomatsuItaru Hamachi
Jul 28, 2009·Journal of the American Chemical Society·Jie GaoZhimou Yang
Apr 10, 2010·Journal of the American Chemical Society·E Thomas PashuckSamuel I Stupp
Feb 18, 2010·Journal of the American Chemical Society·Kerstin M GallerJeffrey D Hartgerink
Jul 9, 2010·Langmuir : the ACS Journal of Surfaces and Colloids·Ye ZhangBing Xu
Feb 5, 2011·Langmuir : the ACS Journal of Surfaces and Colloids·Woo-Jae ChungSeung-Wuk Lee
Apr 15, 2011·Langmuir : the ACS Journal of Surfaces and Colloids·Dimitris MissirlisMatthew Tirrell
Apr 7, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Albert M Hung, Samuel I Stupp
Feb 6, 2009·Nano Letters·Honggang CuiSamuel I Stupp
Feb 10, 2009·Nano Letters·Idit BuchRuth Nussinov
Jul 14, 2011·ACS Nano·Adam W Perriman, Stephen Mann
Nov 3, 2011·ACS Nano·Stephen SoukaseneSamuel I Stupp
Nov 17, 2012·ACS Nano·Shantanu SurSamuel I Stupp
Jun 14, 2013·ACS Nano·Pengcheng ZhangHonggang Cui

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