Peptide-Programmable Nanoparticle Superstructures with Tailored Electrocatalytic Activity

ACS Nano
Eun Sung KangYong Ho Kim

Abstract

Biomaterials derived via programmable supramolecular protein assembly provide a viable means of constructing precisely defined structures. Here, we present programmed superstructures of AuPt nanoparticles (NPs) on carbon nanotubes (CNTs) that exhibit distinct electrocatalytic activities with respect to the nanoparticle positions via rationally modulated peptide-mediated assembly. De novo designed peptides assemble into six-helix bundles along the CNT axis to form a suprahelical structure. Surface cysteine residues of the peptides create AuPt-specific nucleation site, which allow for precise positioning of NPs onto helical geometries, as confirmed by 3-D reconstruction using electron tomography. The electrocatalytic model system, i.e., AuPt for oxygen reduction, yields electrochemical response signals that reflect the controlled arrangement of NPs in the intended assemblies. Our design approach can be expanded to versatile fields to build sophisticated functional assemblies.

References

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Citations

Feb 12, 2020·Quarterly Reviews of Biophysics·Ivan V Korendovych, William F DeGrado
Dec 10, 2019·Advanced Materials·Soumitra Mokashi-PunekarNathaniel L Rosi
Apr 8, 2020·Nanoscale Horizons : the Home for Rapid Reports of Exceptional Significance in Nanoscience and Nanotechnolgy·Dean HoTheodore Kee
Nov 25, 2020·Langmuir : the ACS Journal of Surfaces and Colloids·Jiale LiuHao Zhang
Nov 2, 2021·ACS Applied Materials & Interfaces·Yani PanJanine Mauzeroll

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