Peptide uptake in Candida albicans

Journal of General Microbiology
M B Davies

Abstract

Transport of radioactively labelled peptides has been used to characterize a common transport system for di- and tripeptides in Candida albicans. This permease is energy-dependent and has a requirement for L-amino acid residues, an alpha-linkage between residues and a free amino terminus. Transport was followed by the accumulation inside the cell of intact peptides and component amino acids. After transport of glycyl-[U-14C]phenylalanine the radioactive material was accumulated inside the cell and subsequently leaked into the medium under certain conditions.

Citations

Jun 23, 2005·Journal of Enzyme Inhibition and Medicinal Chemistry·Ryszard AndruszkiewiczAleksandra Walkowiak
Mar 14, 1997·Biochimica Et Biophysica Acta·J Horák

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