PMID: 8584419Nov 1, 1995Paper

Peptide YY release after intraduodenal, intraileal, and intracolonic administration of nutrients in rats

Pflügers Archiv : European journal of physiology
X Fu-ChengC Rozé

Abstract

Peptide YY (PYY) release was studied by measuring radioimmunoassayable PYY in the arterial plasma of anaesthetized rats receiving into the duodenum, ileum or colon either a complete semi-liquid meal (3ml, 21kJ) or elemental nutrients as isocaloric or isoosmolar solutions. PYY release induced by the intraduodenal meal peaked at 60min and lasted more than 120min. The integrated response of PYY over 120min was larger when the meal was administered into the duodenum than into the ileum. The undigested meal induced no release of PYY over a 120-min period when administered into the colon. When injected into the duodenum in isocaloric amounts to the meal, glucose and amino acids led to the release of as much PYY as did the meal, whereas oleic acid led to the release of less PYY. Part of these responses were due to osmolarity, since administration of intraduodenal hyperosmolar saline led to the release of about half as much PYY as did hyperosmolar glucose. In moderate amounts, and injected as a solution isoosmolar to plasma, oleic acid was a major PYY releaser; the amounts released were at least two times larger when oleic acid was administered into the duodenum than into the ileum and colon. Isoosmolar glucose and amino acids led to t...Continue Reading

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Citations

Feb 5, 2002·Peptides·Takenori OnagaSeiyu Kato
May 4, 2002·The Journal of Nutritional Biochemistry·Raul A. Wapnir, Saul Teichberg
Mar 1, 1996·The Proceedings of the Nutrition Society·C Rozé
Nov 1, 2011·Neuropharmacology·Amir H SamGavin A Bewick
Sep 24, 2015·Digestive Diseases and Sciences·Patrick Berg, Richard McCallum
Jun 24, 2008·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Koji MurashitaToshiro Masumoto
Aug 24, 2007·Medical Hypotheses·P Mainardi, C Albano
Feb 3, 2005·Obesity Research·Sulay A TovarCarlos Diéguez
Aug 12, 2014·International Journal of Obesity : Journal of the International Association for the Study of Obesity·A PsichasG Frost
Dec 15, 2012·Endocrinology·Ulrike StadlbauerWolfgang Langhans
Nov 30, 2019·Frontiers in Nutrition·Andreas SteingoetterPeter Fischer
Nov 15, 2017·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Gilliard LachJohn F Cryan
Apr 20, 2005·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·C-H Malbert
Jul 1, 2011·Journal of Pediatric Endocrinology & Metabolism : JPEM·Christian L RothJoachim Woelfle
Oct 29, 2000·American Journal of Physiology. Gastrointestinal and Liver Physiology·G CucheC H Malbert
Apr 14, 2000·American Journal of Physiology. Gastrointestinal and Liver Physiology·T PicheJ P Galmiche
Apr 25, 2017·The Journal of Poultry Science·Kazuhisa HondaHiroshi Kamisoyama
Dec 9, 1998·The American Journal of Physiology·C CherbutJ P Galmiche

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