PMID: 7029493Jan 1, 1981Paper

Peptidergic control of insulin-induced feeding

Peptides
A S Levine, J E Morley

Abstract

Subcutaneous administration of insulin(10 U/kg) produced hypoglycemia in rats with a concomitant induction of feeding. The opiate antagonist naloxone failed to alter food ingestion following insulin administration when quantitated over a 3-hour period; however, naloxone (20 mg/kg) significantly suppressed eating during the first hour of the study. Starvation-induced feeding was markedly suppressed by relatively low doses of naloxone (1 mg/kg). The dopamine antagonist haloperidol, the cholinergic antagonist atropine, and the putative satiety factors CCK-8, bombesin, histidyl-proline diketopiperazine and calcitonin suppressed insulin-induced feeding. Naloxone, CCK-8 and bombesin significantly raised blood glucose levels following insulin induced hypoglycemia.

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Citations

Jan 1, 1988·Psychopharmacology·H C Akunne, K F Soliman
May 28, 1985·European Journal of Pharmacology·J E MorleyG T Shearman
Aug 2, 1982·Life Sciences·J E MorleyS E Silvis
Jun 1, 1982·Physiology & Behavior·A S LevineB S Handwerger
Nov 1, 1982·Physiology & Behavior·D B ClarksonR D Olson
Mar 1, 1983·Physiology & Behavior·J E MorleyU S Seal
Dec 1, 1985·Physiology & Behavior·E D PlotkaU S Seal
Jan 1, 1986·Physiology & Behavior·S E NizielskiB A Gosnell
Jun 1, 1982·Pharmacology, Biochemistry, and Behavior·A S Levine, J E Morley
Jun 1, 1982·Pharmacology, Biochemistry, and Behavior·N Rowland, T J Bartness
May 1, 1982·Pharmacology, Biochemistry, and Behavior·J E MorleyJ Kneip
Jan 1, 1983·Pharmacology, Biochemistry, and Behavior·A S LevineJ E Morley
Oct 1, 1983·Pharmacology, Biochemistry, and Behavior·J E MorleyC J Billington
Nov 1, 1985·Pharmacology, Biochemistry, and Behavior·J M DavisP V Malven
Jan 1, 1985·Pharmacology, Biochemistry, and Behavior·B A Baldwin, R F Parrott
Apr 1, 1986·Pharmacology, Biochemistry, and Behavior·E C SiG K Yim
Mar 1, 1988·Pharmacology, Biochemistry, and Behavior·A S LevineJ E Morley
Feb 1, 1988·Pharmacology, Biochemistry, and Behavior·C R BowdenA J Bean
Aug 1, 1992·Pharmacology, Biochemistry, and Behavior·J E KochR J Bodnar
Jan 1, 1983·Neuroscience and Biobehavioral Reviews·J E MorleyM T Lowy
Aug 1, 1983·Regulatory Peptides·V SchusdziarraE F Pfeiffer
Jan 1, 1982·Peptides·J E MorleyB S Handwerger
May 1, 1983·Peptides·D E NiewoehnerJ E Morley
Jan 1, 1985·Peptides·J E MorleyS E Nizielski
Jul 1, 1991·Peptides·J E Morley, J F Flood
Jun 1, 1985·Brain Research Bulletin·A S LevineT J Bartness
Jun 1, 1985·Brain Research Bulletin·D T FullertonI H Carlson
May 15, 2002·European Journal of Pharmacology·Kazuyuki YamadaKeiji Wada
Jun 1, 1989·British Poultry Science·J F McCormack, D M Denbow
May 30, 1987·British Medical Journal·C Dieguez, M F Scanlon
Jan 1, 1997·Annual Review of Nutrition·A S Levine, C J Billington
Apr 7, 2009·Pharmacology, Biochemistry, and Behavior·Jessica E LayneMark A Cline
Nov 1, 1992·Neuropeptides·A PrasadC Prasad
Jan 1, 1985·Annals of the New York Academy of Sciences·J E MorleyJ J Hughes
Sep 20, 1988·Brain Research·J F Flood, J E Morley

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