PMID: 9175475May 1, 1997Paper

Peptides in membranes: tipping the balance of membrane stability

Trends in Biochemical Sciences
R BrasseurM Rosseneu

Abstract

This review describes a class of peptides that associate with lipids in membranes and are commonly known as 'oblique-orientated peptides'. Owing to an asymmetric distribution of hydrophobic residues along the axis of the alpha-helix, such peptides can destabilize membranes or lipid cores, thereby facilitating such cellular processes as vesicular fusion or protein transport across subcellular compartments, as well as remodelling of lipid cores.

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Citations

May 14, 1999·Journal of Peptide Science : an Official Publication of the European Peptide Society·A SchellerM Bienert
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