PER-1 production in a urinary isolate of Providencia rettgeri

Journal of Chemotherapy
G BaharZ Gülay

Abstract

A Providencia rettgeri strain resistant to extended-spectrum cephalosporins and intermediate to aztreonam was isolated from the urine of a patient hospitalized in the urology clinic of SSK Educational Hospital in Ankara. Clavulanic acid restored the activity of extended-spectrum cephalosporins, suggesting that the strain was harboring an extended-spectrum beta-lactamase. Since the PER-1 enzyme is widespread in Turkey, and had been already detected in a related species such as Proteus mirabilis, the Providencia strain was suspected of harboring a PER-1 enzyme, which was indeed detected by PCR. This is the first description in a P. rettgeri isolate of a PER-1 enzyme which is widespread among Acinetobacter baumanni and Pseudomonas aeruginosa strains in Turkey.

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Citations

Dec 15, 2010·Antimicrobial Agents and Chemotherapy·Il Kwon BaeKyungwon Lee
Apr 28, 2005·Antimicrobial Agents and Chemotherapy·Laurent PoirelPatrice Nordmann
Jul 29, 2005·Antimicrobial Agents and Chemotherapy·Elisabetta Mantengoli, Gian Maria Rossolini
Jan 10, 2018·Antimicrobial Agents and Chemotherapy·Stefano ManciniPatrice Nordmann
Mar 11, 2020·Frontiers in Microbiology·Delphine GirlichThierry Naas

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