Per-Oral Pyloromyotomy (POP) for Medically Refractory Post-Surgical Gastroparesis

Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract
Andrew T StrongKevin El-Hayek

Abstract

Post-surgical gastroparesis (psGP) is putatively related to vagal denervation from either therapeutic transection or inadvertent injury. Here, we present a series of patients undergoing endoscopic per-oral pyloromyotomy (POP) as a treatment for medically refractory psGP. Patients identified from a prospectively maintained database of patients undergoing POP procedures at our institution from January 2016 to January 2018 were included. Surgical history, symptom scores, and gastric emptying studies before and 3 months after POP were additionally recorded. During the study period, 177 POP procedures were performed, of which 38 (21.5%) were for psGP. The study cohort was 84.2% female with a mean body mass index of 27.6 kg/m2 and mean age of 55.2 years. Common comorbidities included hypertension (34.2%), depression (31.6%), and gastroesophageal reflux disease (28.9%). Hiatal/paraesophageal hernia repair (39.5%) or fundoplication (36.8%) preceded psGP diagnosis most often. The mean operative time was 30 ± 20 min. There were no intraoperative complications. Mean postoperative length of stay was 1.2 days. There were two readmissions within 30 days, one for melena and one for dehydration. The mean improvement in total Gastroparesis Symp...Continue Reading

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Citations

Jan 21, 2020·Langenbeck's Archives of Surgery·Arielle Marian LeeSantiago Horgan
Jun 17, 2020·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Lydia S WattsWilliam L Hasler
Mar 14, 2020·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Rajat GargMadhusudhan R Sanaka
Jul 29, 2020·Gastroenterology Clinics of North America·William L Hasler
May 12, 2020·Gastroenterology·Michael Camilleri, Kenton M Sanders
Sep 22, 2021·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Michael Camilleri
Nov 1, 2021·Gastroenterology·Michael Camilleri, Kenton M Sanders

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