Perceived health status in self-reported adolescent idiopathic scoliosis: a survey based on a population of twins

Spine
Mikkel Ø AndersenKirsten O Kyvik

Abstract

A questionnaire-based identification of adolescent idiopathic scoliosis (AIS) patients and measure of Short Form-12 (SF-12) in a big twin-cohort. The purpose was to study the effect that AIS has on the health-related quality of life in the patients. The effect of AIS on the perceived health status is still unclear. All 46,418 twins registered in the Danish Twin Registry born between 1931 and 1982 were sent a questionnaire including SF-12. The questionnaire was returned by 34,944 (75.3%) twins representing 23,204 pairs. A group of 220 subjects considered to have AIS was identified corresponding to a prevalence of 1.05%. In this group, the SF-12 could be calculated in 187 twins. We found the perceived both mental and physical health status from SF-12 to be moderately but significantly worse than in controls. Approximately 75% of the twins with AIS reported to have the same or a better health than their twin- and age-matched peers.

References

Mar 1, 1988·Spine·S A GrubbR W Coonrad
Aug 1, 1983·Clinical Genetics·P MagnusW E Nance
Jun 1, 1995·International Journal of Epidemiology·K O KyvikH Beck-Nielsen
Jan 15, 2000·Spine·K Y Moen, A L Nachemson
Sep 21, 2001·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·A J DanielssonA L Nachemson
Jan 23, 2003·Twin Research : the Official Journal of the International Society for Twin Studies·Axel SkyttheKaare Christensen
Feb 13, 2003·JAMA : the Journal of the American Medical Association·Stuart L WeinsteinIgnacio V Ponseti
Sep 27, 2003·Twin Research : the Official Journal of the International Society for Twin Studies·Lene ChristiansenKirsten Kyvik
Nov 26, 2005·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Karen Petra WeigertCody Bünger
Feb 2, 2006·Spine·Mikkel O AndersenKarsten Thomsen
Apr 13, 2006·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Eveline M BungeUNKNOWN NESCIO group
Apr 12, 2007·Spine·Mikkel O AndersenKirsten O Kyvik

❮ Previous
Next ❯

Citations

Mar 18, 2016·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Massimo MaricondaValeria Servodidio
Mar 3, 2010·Neurosurgical Focus·Lauren E MatteiniJoseph R O'Brien
May 29, 2018·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Altuğ DuramazTayfun Kara

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.