Perceived Stress and Surgical Wound Cytokine Patterns

Plastic Surgical Nursing : Official Journal of the American Society of Plastic and Reconstructive Surgical Nurses
Valentina Sage LucasAndrea L Pozez

Abstract

This was a pilot study to examine pre- and postoperative stress experienced by women who were undergoing autologous breast reconstruction and how stress might impact wound healing, specifically examining cytokines and other chemical mediators in the wound environment. A nonexperimental descriptive design over time was utilized. Participants were women who were undergoing autologous abdominal breast reconstruction for breast cancer (N = 20). Data were collected preoperatively and at 24, 48, 72, and 96 hr postsurgery. Complications were monitored intraoperatively and up to 30 days postsurgery. Psychological stress was measured with the 10-item Perceived Stress Scale (PSS), the Impact of Events Scale-Revised (IES-R), and a 100-mm Visual Analog Scale (VAS). Cytokines were assayed using the 27-plex kit with a Bio-Plex Plus. Although breast cancer is considered a stressor, in this sample of women, scores of the PSS, IES-R, and VAS showed that in fact these participants experienced low levels of psychological stress. All measured biochemical mediators in serum and wound fluid were detected and trends were identified. IL-1ra, IL-6, IL-8, G-CSF, IP-10, MCP-1, MIP-1β, RANTES, and VEGF were present in the highest concentrations. Significa...Continue Reading

References

Jul 1, 1995·The Journal of Investigative Dermatology·E FeikenL R Lund
Apr 1, 1996·Journal of Advanced Nursing·J M ZellerB Swanson
Sep 1, 1996·Nursing Research·J M ZellerM A Colletti
May 8, 1999·Archives of General Psychiatry·R GlaserW B Malarkey
Sep 2, 1999·The New England Journal of Medicine·A J Singer, R A Clark
Apr 12, 2000·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·N J TrengoveM C Stacey
Dec 15, 2000·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·E A Baker, D J Leaper
Jun 8, 2001·The Journal of Immunology : Official Journal of the American Association of Immunologists·R SalcedoJ J Oppenheim
Jul 27, 2001·Current Pharmaceutical Design·M Gharaee-Kermani, S H Phan
Nov 8, 2001·Plastic and Reconstructive Surgery·V K Rumalla, G L Borah
Jan 29, 2002·International Immunopharmacology·Eric V Yang, Ronald Glaser
Mar 15, 2003·Clinics in Plastic Surgery·JoAn L Monaco, W Thomas Lawrence
Jul 9, 2003·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Elizabeth A BakerDavid J Leaper
Sep 3, 2003·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Louis W C ChowCarter Cheng
Sep 26, 2003·Psychosomatic Medicine·Elizabeth BroadbentRoger J Booth
Oct 9, 2003·JAMA : the Journal of the American Medical Association·Chunliu Zhan, Marlene R Miller
Jan 7, 2004·Behaviour Research and Therapy·Mark CreamerSalvina Failla
Apr 20, 2004·The Journal of Burn Care & Rehabilitation·Philip A Efron, Lyle L Moldawer
Jul 14, 2004·Annals of Surgical Oncology·P AnanianC Julian-Reynier
Jul 15, 2004·Psychological Bulletin·Suzanne C Segerstrom, Gregory E Miller
Nov 18, 2005·ANS. Advances in Nursing Science·Nancy L McCainJoLynne Robins
Dec 7, 2005·Archives of General Psychiatry·Janice K Kiecolt-GlaserRonald Glaser
Jul 1, 2006·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Gaetano Di VitaEnrico Cillari
Dec 30, 2006·Brain, Behavior, and Immunity·Shawn F Sorrells, Robert M Sapolsky
Feb 6, 2007·Clinics in Dermatology·Jie LiRobert Kirsner
Feb 6, 2007·Clinics in Dermatology·Loretta Vileikyte
May 4, 2007·Periodontology 2000·Lakshmi Boyapati, Hom-Lay Wang
May 9, 2007·Frontiers in Bioscience : a Journal and Virtual Library· RajaR Rivkah Isseroff
Aug 22, 2007·Neuroimmunomodulation·Lisa M ChristianJanice K Kiecolt-Glaser
Aug 25, 2007·Annual Review of Clinical Psychology·Scott M Monroe
Oct 2, 2007·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Wings T Y LooLouis W C Chow
Dec 1, 2007·The International Journal of Lower Extremity Wounds·Dorne R YagerLaura A Gilman
Dec 19, 2007·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Elizabeth A BakerDavid J Leaper
Mar 4, 2008·The Journal of Bone and Joint Surgery. American Volume·Jonathan Agner ForsbergFrancis Xavier McGuigan
Jan 9, 2009·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Stephan BarrientosMarjana Tomic-Canic
Nov 12, 2009·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Chandan K SenMichael T Longaker
Jan 4, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·B BehmS Schreml
Mar 27, 2012·Clinical Breast Cancer·Jane L MeiselAnn H Partridge
Oct 3, 2012·Current Opinion in Allergy and Clinical Immunology·Anne PuelJean-Laurent Casanova

❮ Previous
Next ❯

Citations

May 15, 2020·Holistic Nursing Practice·Mette Haslund Karoliussen, Reidun Hov
Jun 4, 2020·Cellular Oncology (Dordrecht)·Łukasz ZadkaPiotr Dzięgiel

❮ Previous
Next ❯

Related Concepts

Related Feeds

Arterial-Venous in Development & Disease

Arterial-venous development may play a crucial role in cardiovascular diseases. Here is the latest research.