Abstract
We aimed to replicate and extend our previous findings of an association between percent body fat in recently weight-restored patients with Anorexia Nervosa (AN) and clinical outcome in the year following treatment. Twenty-two hospitalized, weight-restored women with AN underwent whole body MRI to determine percent adipose tissue. Following hospital discharge, patients were contacted regularly, and at the end of the year, clinical outcome was determined using modified Morgan-Russell (MR) criteria: full, good, fair or poor. Identical to our previous study, outcome was dichotomized into "full, good or fair" and "poor" groups. Data from 21 subjects were available for analysis. Percent body fat was significantly lower in the poor outcome group (22% ± 5%) compared to the "full, good or fair" outcome group (27 % ± 4%)(p < 0.035). To further examine the relationship, we combined data from the current study with data from the 26 subjects on whom we had previously reported. Univariate analysis of variance (ANOVA) demonstrated a significant difference in percent adipose tissue across the four MR outcome groups (F = 3.416, df = 3, p<0.03). Lower percent adipose tissue after short-term weight normalization is associated with poor clinical ...Continue Reading
References
Nov 1, 1975·Psychological Medicine·H G Morgan, G F Russell
Jan 1, 1995·Psychological Medicine·E D EckertR Crosby
Mar 1, 1996·The American Journal of Clinical Nutrition·R P Abernathy, D R Black
Jan 1, 1997·Archives of Pediatrics & Adolescent Medicine·N H GoldenI R Shenker
Nov 14, 1997·The International Journal of Eating Disorders·M StroberW Morrell
Jun 25, 1998·Clinical Psychology Review·K M Pike
Jul 19, 2001·Psychological Medicine·B LöweW Herzog
Jan 17, 2003·Obesity Research·Wei ShenSteven B Heymsfield
Apr 22, 2004·Psychological Medicine·J C CarterD B Woodside
Apr 28, 2004·Psychoneuroendocrinology·K HoltkampB Herpertz-Dahlmann
Oct 19, 2005·The International Journal of Eating Disorders·Manfred M FichterSusanne Hedlund
Dec 7, 2005·The American Journal of Psychiatry·Pamela K KeelDavid B Herzog
Jun 15, 2006·JAMA : the Journal of the American Medical Association·B Timothy WalshWendi Rockert
Jun 2, 2007·The American Journal of Psychiatry·Laurel E S MayerB Timothy Walsh
Apr 11, 2008·The American Journal of Clinical Nutrition·Janet E SchebendachB Timothy Walsh
May 6, 2008·The International Journal of Eating Disorders·Christina A RobertoB Timothy Walsh
Jun 24, 2008·Nordic Journal of Psychiatry·Loa Clausen
Oct 10, 2008·The American Journal of Clinical Nutrition·Rebecca ScherzerUNKNOWN Study of Fat Redistribution Metabolic Change in HIV Infection
Oct 11, 2008·Psychological Medicine·A S KaplanM Parides
Apr 22, 2009·Psychological Bulletin·Jennifer J ThomasKelly D Brownell