Perceptions and Attitudes Towards Medication Adherence during Pregnancy in Inflammatory Bowel Disease

Journal of Crohn's & Colitis
Zane R GallingerGeoffrey C Nguyen

Abstract

Women with inflammatory bowel disease [IBD] report concerns about medication safety during pregnancy. Adherence to IBD medications may be lower in pregnant patients as a result. The aim of this study was to assess medication adherence during pregnancy in women with inflammatory bowel disease. Female patients of childbearing age completed a self-administered, structured survey. We collected demographic data, medication history, and self-reported adherence to IBD medications during pregnancy. We also assessed knowledge and perceptions of IBD medication safety in pregnancy. A time trade-off [TTO] analysis was done to assess health utilities for continuing or discontinuing IBD medications during pregnancy. A total of 204 women completed the survey [mean age was 32.8 years]. Current or previous pregnancy was reported by 101 patients [median parity 2, median gravity 1]. While pregnant or attempting to conceive, 47 [46.5%] participants reported stopping a prescribed IBD medication. Of those, 20 participants reported stopping medications without the advice of a physician. TTO analysis was completed by 31 patients. When presented with the option of continuing a potentially teratogenic medication, switching to less effective medication t...Continue Reading

References

Apr 1, 1989·American Journal of Obstetrics and Gynecology·D M FedorkowC A Nimrod
Apr 14, 2000·The American Journal of Gastroenterology·M A MoserR J Bailey
Apr 3, 2002·The American Journal of Gastroenterology·Jason A DominitzEdward J Boyko
Jul 23, 2003·The American Journal of Gastroenterology·Maida J SewitchPatricia L Dobkin
Apr 20, 2004·The American Journal of Gastroenterology·David Norman MoskovitzDaniel H Present
Jan 9, 2007·Inflammatory Bowel Diseases·Sheetal R MarriAlan L Buchman
Apr 18, 2007·The American Journal of Gastroenterology·Jason P EdigerCharles N Bernstein
Apr 9, 2010·Alimentary Pharmacology & Therapeutics·M J NielsenL A Christensen
Dec 3, 2010·Journal of Crohn's & Colitis·R E MountifieldJ M Andrews
Dec 3, 2010·Journal of Crohn's & Colitis·C Janneke van der WoudeUNKNOWN European Crohn's Colitis Organisation (ECCO)
Jul 19, 2011·International Journal of Colorectal Disease·Siraj G RajaratnamNicola S Fearnhead
Sep 6, 2013·Alimentary Pharmacology & Therapeutics·N TavernierC Gower-Rousseau
Jan 21, 2015·Journal of Crohn's & Colitis·C J van der WoudeUNKNOWN European Crohn’s and Colitis Organization
Dec 22, 2015·Gastroenterology·Geoffrey C NguyenUNKNOWN Canadian Association of Gastroenterology

❮ Previous
Next ❯

Citations

May 22, 2016·Journal of Crohn's & Colitis·C Janneke van der Woude, Shannon L Kanis
Jan 29, 2020·Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates·Simon R Knowles, George Alex
Apr 15, 2020·Alimentary Pharmacology & Therapeutics·Robyn Laube, Christian P Selinger
Mar 16, 2018·European Journal of Gastroenterology & Hepatology·Jildou HoekstraRachel L West
Dec 5, 2019·Alimentary Pharmacology & Therapeutics·Sangmin LeeAmy Metcalfe
Apr 9, 2017·Scandinavian Journal of Gastroenterology·Ko Eun LeeSuk-Kyun Yang
Nov 10, 2018·Alimentary Pharmacology & Therapeutics·Satvinder PurewalMatthew J Brookes
Jan 9, 2020·Alimentary Pharmacology & Therapeutics·Parul TandonVivian Huang
Jul 22, 2020·Digestive Diseases and Sciences·Aiya AboubakrMarla C Dubinsky
Oct 24, 2020·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Yael LurieDaniel Kurnik
Aug 18, 2020·European Journal of Gastroenterology & Hepatology·Francesc CasellasEstíbaliz Loza
Nov 13, 2020·Thyroid : Official Journal of the American Thyroid Association·Freddy J K TolozaSpyridoula Maraka
Jan 8, 2021·Expert Opinion on Drug Safety·Robyn LaubeRupert W Leong
Dec 19, 2019·Journal of the Canadian Association of Gastroenterology·Reed T SuttonVivian W Huang
Jun 15, 2021·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·UNKNOWN Italian Group for the Study of Inflammatory Bowel Disease Working Group:Alessia Todeschini
Oct 25, 2021·American Journal of Obstetrics & Gynecology MFM·Patricia RekawekMaria T Mella

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.