Perceptions of HIV cure research among people living with HIV in Australia

PloS One
Jennifer PowerJacqui Richmond

Abstract

Participation in HIV cure-related clinical trials that involve antiretroviral treatment (ART) interruption may pose substantial individual risks for people living with HIV (PLHIV) without any therapeutic benefit. As such, it is important that the views of PLHIV are considered in the design of HIV cure research trials. Examining the lived experience of PLHIV provides unique and valuable perspectives on the risks and benefits of HIV cure research. In this study, we interviewed 20 PLHIV in Australia about their knowledge and attitudes toward clinical HIV cure research and explored their views regarding participation in HIV cure clinical trials, including those that involve ART interruption. Data were analysed thematically, using both inductive and deductive coding techniques, to identity themes related to perceptions of HIV cure research and PLHIV's assessment of the possible risks and benefits of trial participation. Study findings revealed interviewees were willing to consider participation in HIV cure research for social reasons, most notably the opportunity to help others. Concerns raised about ART interruption related to the social and emotional impact of viral rebound, including fear of onward HIV transmission and anxiety ab...Continue Reading

References

Oct 6, 2005·Qualitative Health Research·Hsiu-Fang Hsieh, Sarah E Shannon
Oct 21, 2011·AIDS Education and Prevention : Official Publication of the International Society for AIDS Education·Susan KippaxJohn de Wit
Mar 19, 2014·Virology·Caroline P Passaes, Asier Sáez-Cirión
Sep 27, 2014·AIDS Research and Human Retroviruses·Jenny Louise AndersonAnna Laura Ross
Oct 5, 2014·Trends in Microbiology·Karine DubéDavid M Margolis
Jul 18, 2015·Qualitative Health Research·Janice M Morse
Aug 5, 2015·AIDS Education and Prevention : Official Publication of the International Society for AIDS Education·Daniel GraceMark Gilbert
Dec 9, 2015·Trends in Microbiology·Cynthia I GrossmanUNKNOWN International AIDS Society (IAS) ‘Towards an HIV Cure’ initiative
May 12, 2016·HIV Medicine·R SimmonsUNKNOWN Collaborative HIV Eradication of viral Reservoirs (CHERUB) Survey collaboration
Jul 12, 2016·Nature Medicine·Steven G DeeksJerome Zack
Aug 18, 2016·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Susan H EshlemanMyron S Cohen
Dec 3, 2016·AIDS Research and Human Retroviruses·Syamalima DubeBernard J Poiesz
Aug 14, 2015·Global Qualitative Nursing Research·Michele J McIntosh, Janice M Morse
Jul 1, 2017·The Journal of Law, Medicine & Ethics : a Journal of the American Society of Law, Medicine & Ethics·Macey L Henderson, Jed Adam Gross

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Citations

Feb 27, 2020·Current Opinion in HIV and AIDS·Jeremy Sugarman
Oct 31, 2019·Journal of the International AIDS Society·Karine DubéPaul Gaist
Jan 31, 2021·Journal of Clinical Epidemiology·Patrizia NataleAllison Tong
Feb 19, 2021·Journal of Virus Eradication·Marie-Angélique De ScheerderLinos Vandekerckhove
Jul 2, 2021·BMC Medical Ethics·Karine DubéJeremy Sugarman

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Methods Mentioned

BETA
biopsies

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