Schizophrenia patients' perceptual organization abilities were assessed with a psychophysically well-controlled measure of contour integration. Compared with psychiatric and staff controls, schizophrenia patients were less able to detect contours comprising Gabor elements as the detection of these contours relied increasingly on long-range spatial interactions. Impaired task performance was also found to correlate significantly with higher levels of disorganized symptomatology. These data provide further evidence for impaired perceptual grouping in schizophrenia. In addition, the findings support the hypothesis that a common cortical processing algorithm involving contextual coordination is impaired in schizophrenia, leading to reduced binding of object features in vision, and reduced contextual disambiguation of linguistic information during thought and speech.
Dot Enumeration Perceptual Organization Task (DEPOT): evidence for a short-term visual memory deficit in schizophrenia
How does the cerebral cortex work? Learning, attention, and grouping by the laminar circuits of visual cortex
A new test of contour integration deficits in patients with a history of disrupted binocular experience during visual development
The computation of occluded contours in visual agnosia: Evidence for early computation prior to shape binding and figure-ground coding
NMDA receptor antagonists distort visual grouping in rats performing a modified two-choice visual discrimination task
Poor premorbid social functioning and theory of mind deficit in schizophrenia: evidence of reduced context processing?
Reduced facilitation effect of collinear flankers on contrast detection reveals impaired lateral connectivity in the visual cortex of schizophrenia patients
Synchronous gamma activity: a review and contribution to an integrative neuroscience model of schizophrenia
Recovery from psychosis in schizophrenia and schizoaffective disorder: symptoms and neurocognitive rate-limiters for the development of social behavior skills
Perceptual organization in schizophrenia spectrum disorders: empirical research and theoretical implications
Reduced crowding and poor contour detection in schizophrenia are consistent with weak surround inhibition
The visual search analogue of latent inhibition: implications for theories of irrelevant stimulus processing in normal and schizophrenic groups
The course and clinical correlates of dysfunctions in visual perceptual organization in schizophrenia during the remission of psychotic symptoms
Histories of childhood maltreatment in schizophrenia: relationships with premorbid functioning, symptomatology, and cognitive deficits
Encoding dysfunctions in a dynamic-static paradigm for visuospatial working memory in first-episode psychosis patients: a 2-year follow-up study
Abnormal context-reward associations in an immune-mediated neurodevelopmental mouse model with relevance to schizophrenia
Jung's views on causes and treatments of schizophrenia in light of current trends in cognitive neuroscience and psychotherapy research I. Aetiology and phenomenology
Electrophysiological correlates of local-global visual processing in college students with schizotypal traits: an event-related potential study
Hierarchical Classes Analysis (HICLAS): A novel data reduction method to examine associations between biallelic SNPs and perceptual organization phenotypes in schizophrenia
Is disorganization a feature of schizophrenia or a modifying influence: evidence of covariation of perceptual and cognitive organization in a non-patient sample
MK-801 Impairs Cognitive Coordination on a Rotating Arena (Carousel) and Contextual Specificity of Hippocampal Immediate-Early Gene Expression in a Rat Model of Psychosis
Seeing more clearly through psychosis: Depth inversion illusions are normal in bipolar disorder but reduced in schizophrenia
The effects of familiarity and emotional expression on face processing examined by ERPs in patients with schizophrenia
Emotional context processing in severe mental illness: scale development and preliminary construct validity
Perceptual organization in ketamine users: preliminary evidence of deficits on night of drug use but not 3 days later
Both unmedicated and medicated individuals with schizophrenia show impairments across a wide array of cognitive and reinforcement learning tasks
Genetic and Developmental Perspective of Language Abnormality in Autism and Schizophrenia: One Disease Occurring at Different Ages in Humans?
Reduced influence of perceptual context in schizophrenia: behavioral and neurophysiological evidence
Is 20/20 vision good enough? Visual acuity differences within the normal range predict contour element detection and integration
A Role for Somatostatin-Positive Interneurons in Neuro-Oscillatory and Information Processing Deficits in Schizophrenia
Intact perception of coherent motion, dynamic rigid form, and biological motion in chronic schizophrenia
Multiple forms of contour grouping deficits in schizophrenia: what is the role of spatial frequency?
Improving cognition in severe mental illness by combining cognitive remediation and transcranial direct current stimulation: study protocol for a pragmatic randomized controlled pilot trial (HEADDSET).
Anti-N-Methyl-D-Aspartate Receptor Encephalitis
Anti-N-Methyl-D-Aspartate (NMDA) receptor encephalitis is a form of of brain inflammation due to antibodies against NMDA receptors. Discover the latest research on anti-NMDA receptor encephalitis here.